Document Detail

Effects of different forms of aprotinin during cardiopulmonary bypass.
MedLine Citation:
PMID:  7694437     Owner:  NLM     Status:  MEDLINE    
Effects of two different forms of aprotinin on postoperative blood loss and need for blood replacement were compared in patients undergoing cardiac surgery. One group (n = 46) received 2.10(6) KIA aprotinin (Trasylol), the other group (n = 46) received 2.10(6) PIU aprotinin (Iniprol). Blood loss during the first 12 hours postoperatively was similar (704 +/- 59 ml and 701 +/- 93 ml respectively). Amount of postoperatively transfused blood, fresh frozen plasma, platelets, plasma expanders and fluids was comparable in both groups. Effects of cardiopulmonary bypass on aPTT, PTT, fibrinogen and platelet count were also similar.
A De Bakker; S De Hert; R Vlaeminck; G Delrue; E Govaerts; K Vermeyen
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta anaesthesiologica Belgica     Volume:  44     ISSN:  0001-5164     ISO Abbreviation:  Acta Anaesthesiol Belg     Publication Date:  1993  
Date Detail:
Created Date:  1993-12-01     Completed Date:  1993-12-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0421022     Medline TA:  Acta Anaesthesiol Belg     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  45-51     Citation Subset:  IM    
Department of Anesthesia, University Hospital Antwerp, Belgium.
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MeSH Terms
Aprotinin / pharmacology*
Blood Coagulation / drug effects
Blood Loss, Surgical*
Blood Transfusion
Cardiopulmonary Bypass*
Coronary Artery Bypass
Fluid Therapy
Middle Aged
Plasma Substitutes
Platelet Count / drug effects
Reg. No./Substance:
0/Plasma Substitutes; 9087-70-1/Aprotinin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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