Document Detail

Effects of dietary mannan oligosaccharide, bacitracin methylene disalicylate, or both on the live performance and intestinal microbiology of turkeys.
MedLine Citation:
PMID:  15285506     Owner:  NLM     Status:  MEDLINE    
Hybrid male turkeys were fed to 18 wk of age in a completely randomized design with 10 replicate pens (18 birds each) per treatment to compare growth promoters. Four dietary treatments were used: negative control (CON), bacitracin methylene disalicyate (BMD) at 55 mg/kg to 6 wk and 27.5 mg/kg thereafter, mannan oligosaccharide (MOS) at 0.1% to 6 wk and 0.05% thereafter, and BMD and MOS at concentrations listed above. There were 3 toms/m2 (3.59 ft2/tom) on fresh pine shavings inoculated with used litter. A 6-phase feeding program was used, with crumbles the first 3 wk and pellets thereafter. At wk 6 and 18, one bird per pen was killed, and the large intestinal microbial populations, after being frozen, were enumerated (i.e., bifidobacteria, Clostridium perfringens, coliforms, enterococci, Escherichia coli, lactobacilli, and total anerobes). Body weights at wk 18 were as follows: CON, 11.87 kg; BMD, 12.46 kg; MOS: 12.56 kg; and BMD + MOS, 12.79 kg. The BMD and MOS turkeys were (P < 0.05) heavier than CON birds, and those fed the combination were significantly heavier than all other treatments. At wk 18, BMD + MOS feed conversion ratio of 2.66 was significantly lower than CON at 3.00 with BMD and MOS being intermediate (2.83 and 2.79, respectively). Mortality was not affected by treatment. The BMD and MOS each reduced large intestinal concentrations of Clostridium perfringens (log transformed data analysis) at wk 6 but not at wk 18. The BMD or MOS each improved turkey performance, and when used together, exhibited further beneficial effects.
M D Sims; K A Dawson; K E Newman; P Spring; D M Hoogell
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Poultry science     Volume:  83     ISSN:  0032-5791     ISO Abbreviation:  Poult. Sci.     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-08-02     Completed Date:  2004-10-14     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0401150     Medline TA:  Poult Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1148-54     Citation Subset:  IM    
Virginia Scientific Research, Inc., Harrisonburg, Virginia 22801, USA.
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MeSH Terms
Animal Nutritional Physiological Phenomena
Bacitracin / administration & dosage*
Body Weight
Clostridium perfringens / isolation & purification
Hybridization, Genetic
Intestines / anatomy & histology,  microbiology*
Mannans / administration & dosage*
Oligosaccharides / administration & dosage*
Salicylates / administration & dosage*
Turkeys / anatomy & histology,  microbiology*,  physiology*
Reg. No./Substance:
0/Mannans; 0/Oligosaccharides; 0/Salicylates; 1405-87-4/Bacitracin; 55852-84-1/bacitracin methylenedisalicylic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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