| Effects of dietary fats on nucleoside triphosphatase activity and nuclear membrane fatty acid composition of rats during development. | |
| | |
MedLine Citation:
|
PMID: 7979166 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The effect of various dietary fats on the nucleoside triphosphatase (NTPase) activity and nuclear membrane lipid composition of rat liver during development was assessed. Rats fed a fat-free diet exhibited higher specific activity of NTPase at all ages, compared with control animals. In rats fed a sunflower oil diet, the specific activity of NTPase was also found to be highest at all ages than was observed in the control group. In contrast, animals fed the fish oil diet or peanut-rapeseed oil diet showed a decrease in NTPase activity in comparison with the control group. The specific activity of NTPase was correlated positively with dietary sigma PUFA n-6 (r = 0.03, p < 0.05) and negatively with the dietary sigma PUFA n-3 (r = -0.87; p < 0.05). The fatty acid composition of liver nuclear membranes of rats fed a fat-free diet revealed high levels of 16:1 n-9, 18:1 n-9, and 20:3 n-9 acids. A dramatic decrease in 18:2 n-6, 20:4 n-6, and 22:6 n-3 acids was observed. Animals fed a sunflower oil diet showed high levels of n-6 fatty acids, particularly 22:4 n-6 and 22:5 n-6, and low levels of monounsaturated fatty acids. However, when rats were fed a fish oil diet, the liver nuclear membranes were highly enriched in 20:5 n-3, and 22:6 n-3 acids, and there was a simultaneous decrease in arachidonic acid. From these observations it is concluded that dietary fats induce changes not only in the fatty acid composition of the nuclear membrane lipids but also in the specific activity of NTPase involved in nuclear function. |
| | |
Authors:
|
A Ammouche; Y Youyou; G Durand; J M Bourre |
Related Documents
:
|
8093816 - Function of dietary polyunsaturated fatty acids in the nervous system. 10841036 - Dietary docosahexaenoic acid but not eicosapentaenoic acid suppresses lipopolysaccharid... 20685946 - Effect of long-chain polyunsaturated fatty acid supplementation during pregnancy or lac... 9438236 - Dietary fatty acid profile affects endurance in rats. 7127196 - Tolerance of young turkey poults to various combinations of dietary furazolidone and salt. 6407256 - Maximum calorie (sub-threshold) dieting of the obese and its hormonal response. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Annals of nutrition & metabolism Volume: 38 ISSN: 0250-6807 ISO Abbreviation: Ann. Nutr. Metab. Publication Date: 1994 |
Date Detail:
|
Created Date: 1994-12-02 Completed Date: 1994-12-02 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8105511 Medline TA: Ann Nutr Metab Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 132-40 Citation Subset: IM |
Affiliation:
|
INSERM U-26, Hôpital Fernand-Widal, Paris, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenosine Triphosphatases
/
metabolism* Animals Dietary Fats / administration & dosage, pharmacology* Fatty Acids / metabolism* Fish Oils / pharmacology Liver / enzymology, growth & development*, ultrastructure Male Nuclear Envelope / metabolism* Plant Oils / pharmacology Rats Rats, Sprague-Dawley |
| Chemical | |
Reg. No./Substance:
|
0/Dietary Fats; 0/Fatty Acids; 0/Fish Oils; 0/Plant Oils; 8001-21-6/sunflower seed oil; 8002-03-7/arachis oil; 8002-13-9/rapeseed oil; EC 3.6.1.-/Adenosine Triphosphatases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Effects of dietary proteins and yeast Saccharomyces cerevisiae on vitamin B6 status during growth.
Next Document: Ultrastructure of the heart muscle in rats under hypobaric stress and under high NaCl intake.