| Effects of dietary bread crust Maillard reaction products on calcium and bone metabolism in rats. | |
| | |
MedLine Citation:
|
PMID: 22109787 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Maillard reaction products (MRP) consumption has been related with the development of bone degenerative disorders, probably linked to changes in calcium metabolism. We aimed to investigate the effects of MRP intake from bread crust on calcium balance and its distribution, and bone metabolism. During 88 days, rats were fed control diet or diets containing bread crust as source of MRP, or its soluble high molecular weight, soluble low molecular weight or insoluble fractions (bread crust, HMW, LMW and insoluble diets, respectively). In the final week, a calcium balance was performed, then animals were sacrified and some organs removed to analyse calcium levels. A second balance was carried out throughout the experimental period to calculate global calcium retention. Biochemical parameters and bone metabolism markers were measured in serum or urine. Global calcium bioavailability was unmodified by consumption of bread crust or its isolate fractions, corroborating the previously described low affinity of MRP to bind calcium. Despite this, a higher calcium concentration was found in femur due to smaller bones having a lower relative density. The isolate consumption of the fractions altered some bone markers, reflecting a situation of increased bone resorption or higher turnover; this did not take place in the animals fed the bread crust diet. Thus, the bread crust intake does not affect negatively calcium bioavailability and bone metabolism. |
| | |
Authors:
|
Irene Roncero-Ramos; Cristina Delgado-Andrade; Ana Haro; Beatriz Ruiz-Roca; Francisco J Morales; María Pilar Navarro |
Related Documents
:
|
3453187 - The relationship between diuretics and serum cholesterol in hypertension detection and ... 7193537 - An optically clear hypercholesterolemic hypertriglyceridemic quality-control material p... 12612157 - Food products containing free tall oil-based phytosterols and oat beta-glucan lower ser... 7246527 - Serum cholesterol and mortality: the yugoslavia cardiovascular disease study. 1942307 - A new model of nephrolithiasis involving tubular dysfunction/injury. 2511017 - Risk factors for coronary artery disease: a study comparing hypercholesterolaemia and h... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-11-23 |
Journal Detail:
|
Title: Amino acids Volume: - ISSN: 1438-2199 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
|
Created Date: 2011-11-23 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9200312 Medline TA: Amino Acids Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Instituto en Formación de Nutrición Animal, EEZ-CSIC, Camino del Jueves s/n, 18100, Armilla, Granada, Spain. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Elite premenarcheal rhythmic gymnasts demonstrate energy and dietary intake deficiencies during peri...
Next Document: Targeting radioresistant osteosarcoma cells with parthenolide.