Document Detail


Effects of dietary L-arginine intake on cardiorespiratory and metabolic adaptation in athletes.
MedLine Citation:
PMID:  19827461     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To assess the effect of diet enrichment with L-arginine or supplementation at high doses on physiological adaptation during exercise, 9 athletes followed 3 different diets, each over 3 consecutive days, with a wash-out period of 4 d between training sessions: control diet (CD), 5.5 +/- 0.3 g/d of L-arginine; Diet 1 (rich in L-arginine food), 9.0 +/- 1.1 g/d of L-arginine; and Diet 2 (the same as CD but including an oral supplement of 15 g/d), 20.5 +/- 0.3 g/d of L-arginine. Plasma nitrate levels of each participant were determined on the day after each treatment. Participants performed a submaximal treadmill test (initial speed 10-11 km/hr, work increments 1 km/hr every 4 min until 85-90% VO2max, and passive recovery periods of 2 min). Oxygen uptake and heart rate were monitored throughout the test. Blood lactate concentration ([La-]b) was determined at the end of each stage. Repeated-measures ANOVA and paired Student's t tests were used to compare the various physiological parameters between diets. The level of significance was set at p < .05. [La-]b showed a significant effect at the 5-min time point between CD and Diet 2 (CD 3.0 +/- 0.5 mM, Diet 2 2.5 +/- 0.5 mM, p = .03), but this tendency was not found at higher exercise intensities. No significant differences were observed in any of the cardiorespiratory or plasma nitrate levels. In conclusion, dietary L-arginine intake on the days preceding the test does not improve physiological parameters during exercise.
Authors:
Raul Bescós; Carlos Gonzalez-Haro; Pere Pujol; Franchek Drobnic; Eulalia Alonso; Maria Luisa Santolaria; Olga Ruiz; Marc Esteve; Pedro Galilea
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of sport nutrition and exercise metabolism     Volume:  19     ISSN:  1526-484X     ISO Abbreviation:  Int J Sport Nutr Exerc Metab     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-10-15     Completed Date:  2009-11-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100939812     Medline TA:  Int J Sport Nutr Exerc Metab     Country:  United States    
Other Details:
Languages:  eng     Pagination:  355-65     Citation Subset:  IM    
Affiliation:
Physiology Laboratory, National Institute of Physical Education, Barcelona, Spain.
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MeSH Terms
Descriptor/Qualifier:
Adaptation, Physiological / drug effects*,  physiology
Adolescent
Analysis of Variance
Arginine / administration & dosage,  metabolism,  pharmacology*
Cross-Over Studies
Dietary Supplements
Exercise Test
Food, Fortified
Heart Rate / drug effects*,  physiology
Humans
Lactic Acid / blood*
Male
Nitrates / blood*
Oxygen Consumption / drug effects*,  physiology
Chemical
Reg. No./Substance:
0/Nitrates; 50-21-5/Lactic Acid; 74-79-3/Arginine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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