Document Detail


Effects of diet macronutrient composition on body composition and fat distribution during weight maintenance and weight loss.
MedLine Citation:
PMID:  23671029     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Qualitative aspects of diet may affect body composition and propensity for weight gain or loss. We tested the hypothesis that consumption of a relatively low glycemic load (GL) diet would reduce total and visceral adipose tissue under both eucaloric and hypocaloric conditions.
DESIGN AND METHODS: Participants were 69 healthy overweight men and women. Body composition was assessed by DXA and fat distribution by CT scan at baseline, after 8 weeks of a eucaloric diet intervention, and after 8 weeks of a hypocaloric (1000 kcal/day deficit) diet intervention. Participants were provided all food for both phases, and randomized to either a low GL diet (<45 points per 1000 kcal; n = 40) or high GL diet (>75 points per 1000 kcal, n = 29).
RESULTS: After the eucaloric phase, participants who consumed the low GL diet had 11% less intra-abdominal fat (IAAT) than those who consumed the high GL diet (P < 0.05, adjusted for total fat mass and baseline IAAT). Participants lost an average of 5.8 kg during the hypocaloric phase, with no differences in the amount of weight loss with diet assignment (P = 0.39). Following weight loss, participants who consumed the low GL diet had 4.4% less total fat mass than those who consumed the high GL diet (P < 0.05, adjusted for lean mass and baseline fat mass).
CONCLUSIONS: Consumption of a relatively low GL diet may affect energy partitioning, both inducing reduction in IAAT independent of weight change, and enhancing loss of fat relative to lean mass during weight loss.
Authors:
Amy M Goss; Laura Lee Goree; Amy C Ellis; Paula C Chandler-Laney; Krista Casazza; Mark E Lockhart; Barbara A Gower
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2013-05-13
Journal Detail:
Title:  Obesity (Silver Spring, Md.)     Volume:  21     ISSN:  1930-739X     ISO Abbreviation:  Obesity (Silver Spring)     Publication Date:  2013 Jun 
Date Detail:
Created Date:  2013-08-05     Completed Date:  2014-02-28     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  101264860     Medline TA:  Obesity (Silver Spring)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1139-42     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 The Obesity Society.
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MeSH Terms
Descriptor/Qualifier:
Absorptiometry, Photon
Adult
Blood Glucose / metabolism
Body Composition*
Body Fat Distribution*
Diet Records
Diet, Reducing*
Energy Intake
Female
Follow-Up Studies
Food Habits*
Glycemic Index
Humans
Intervention Studies
Intra-Abdominal Fat
Male
Middle Aged
Overweight / diet therapy
Weight Gain
Weight Loss*
Young Adult
Grant Support
ID/Acronym/Agency:
M01-RR-00032/RR/NCRR NIH HHS; P30 DK056336/DK/NIDDK NIH HHS; P30-DK56336/DK/NIDDK NIH HHS; P60DK079626/DK/NIDDK NIH HHS; R01 DK067538/DK/NIDDK NIH HHS; R01DK67538/DK/NIDDK NIH HHS; UL1 RR025777/RR/NCRR NIH HHS; UL1RR025777/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Blood Glucose
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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