Document Detail


Effects of dengue fever during pregnancy in French Guiana.
MedLine Citation:
PMID:  10194092     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To determine the effects of dengue fever (DF) during pregnancy, pregnant women presenting with a dengue-like syndrome at a hospital in Saint-Laurent du Maroni, French Guiana, from 1 January 1992 to 1 April 1998 were studied. The diagnosis of DF was made by serological tests, virus isolation on AP 61 mosquito cells, and/or reverse transcriptase polymerase chain reaction analysis. Twenty-two women had either probable or confirmed DF. Dengue virus serotype 2 was detected in four cases, and dengue virus serotype 1 was detected in one. Three fetuses died following the onset of the disease, and three cases of prematurity occurred. All infants appeared normal during physical examination, and no neonatal DF was diagnosed. In conclusion, DF in pregnant women did not cause any infant abnormality, but it may have been responsible for fetal death. The rate of fetal death associated with DF (13.6%) was much higher than the mean rate for the gynecology unit at the hospital (1.9%). However, these differences were not significant, and consequently these preliminary results need to be confirmed.
Authors:
G Carles; H Peiffer; A Talarmin
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America     Volume:  28     ISSN:  1058-4838     ISO Abbreviation:  Clin. Infect. Dis.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-06-24     Completed Date:  1999-06-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9203213     Medline TA:  Clin Infect Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  637-40     Citation Subset:  IM    
Affiliation:
Service de Gynécologie-Obstétrique, Hôpital André Bouron, Saint-Lurent du Maroni, French Guiana.
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MeSH Terms
Descriptor/Qualifier:
Dengue / physiopathology*,  virology
Dengue Virus / isolation & purification
Female
Fetal Death / etiology*
French Guiana
Humans
Pregnancy
Pregnancy Complications, Infectious / physiopathology*,  virology
Pregnancy Outcome*
RNA, Viral / analysis
Serologic Tests
Chemical
Reg. No./Substance:
0/RNA, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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