Document Detail

Effects of a daytime infusion of exogenous insulin on subsequent nocturnal food intake and body weight in rats.
MedLine Citation:
PMID:  6348813     Owner:  NLM     Status:  MEDLINE    
Normal rats with chronic cardiac catheters were infused with regular insulin at various doses (0.1 to 0.6 IU/hr). The insulin infusion was limited to the 12 light hours and repeated for 4 consecutive days. Daytime insulin infusion increased the 12 hr cumulative food intake in a dose-dependent fashion. This increase was associated with a compensatory decrease in the subsequent nocturnal intake, so that the 24 hr food intake remained unchanged. Results are discussed in relation to mechanisms involved in the normal circadian rhythms of feeding.
C Larue-Achagiotis; J Le Magnen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiology & behavior     Volume:  30     ISSN:  0031-9384     ISO Abbreviation:  Physiol. Behav.     Publication Date:  1983 Apr 
Date Detail:
Created Date:  1983-09-23     Completed Date:  1983-09-23     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0151504     Medline TA:  Physiol Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  573-6     Citation Subset:  IM    
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MeSH Terms
Body Weight / drug effects*
Circadian Rhythm
Dose-Response Relationship, Drug
Feeding Behavior / drug effects*
Insulin / pharmacology*
Rats, Inbred Strains
Reg. No./Substance:

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