| Effects of coronary artery disease on the aging heart: observations from cardiac catheterization. | |
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MedLine Citation:
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PMID: 6699371 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We evaluated catheterization laboratory data from 691 individuals (219 normals and 472 coronary patients) using a computerized data file that provided several measures of cardiovascular performance in 10-year age increments. The expected increase in arterial pressure with age was noted in normals and coronary patients. Left ventricular end diastolic pressure, end diastolic volume, and end systolic volume remained constant with age but were higher in all age groups in the coronary patients. Ejection fraction showed no change with age but was lower in all age groups in patients with coronary disease. Left ventricular mass increased with age in normals and coronary patients. Cardiac index declined with age, whereas arteriovenous oxygen difference and oxygen consumption were unchanged. Age-related changes in the circulation were for the most part unaffected by the presence of coronary disease. Resting left ventricular function was not altered by age but coronary disease produced a decline in left ventricular function in all ages. |
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Authors:
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E N Bodurian; W P Santamore; A A Bove |
Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Journal of gerontology Volume: 39 ISSN: 0022-1422 ISO Abbreviation: J Gerontol Publication Date: 1984 Mar |
Date Detail:
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Created Date: 1984-04-18 Completed Date: 1984-04-18 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0374762 Medline TA: J Gerontol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 170-7 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aging* Blood Pressure Coronary Disease / physiopathology* Female Heart / physiopathology* Heart Catheterization Heart Rate Hemodynamics* Humans Male Middle Aged Myocardial Contraction Oxygen / physiology Respiration Vascular Resistance |
| Grant Support | |
ID/Acronym/Agency:
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HL 28473/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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