Document Detail

Effects of coronary-artery bypass on global and regional left ventricular function during exercise.
MedLine Citation:
PMID:  306578     Owner:  NLM     Status:  MEDLINE    
To determine the effect of coronary revascularization on exercise-induced abnormalities of left ventricular-ejection fraction and regional contraction, we obtained electrocardiograph-gated 99mTc radionuclide cineangiograms before and after operation in 23 consecutive patients. At rest, their average ejection fraction remained unchanged: 51 +/- 3 versus 54 +/- 4 per cent (+/- S.E.M.). However, 17 of the patients showed improvement of ejection fraction during postoperative exercise (increase of 51 per cent). The remaining six patients had no change or a decreased ejection fraction during exercise. All patients with improved ejection fractions during exercise were symptomatically improved. No improvement of regional function occurred at rest, but improvement did occur in regions of exercise-induced dysfunction. Although coronary revascularization has little effect on left ventricular function at rest, the ejection fraction during exercise and exercise-induced wall-motion abnormalities improve in most patients who experience symptomatic improvement.
K M Kent; J S Borer; M V Green; S L Bacharach; C L McIntosh; D M Conkle; S E Epstein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The New England journal of medicine     Volume:  298     ISSN:  0028-4793     ISO Abbreviation:  N. Engl. J. Med.     Publication Date:  1978 Jun 
Date Detail:
Created Date:  1978-07-24     Completed Date:  1978-07-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0255562     Medline TA:  N Engl J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1434-9     Citation Subset:  AIM; IM; S    
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MeSH Terms
Angina Pectoris / surgery
Blood Pressure
Cardiac Output
Coronary Angiography
Coronary Artery Bypass*
Coronary Disease / radionuclide imaging
Coronary Vessels / radionuclide imaging
Heart / physiology*
Heart Rate
Middle Aged
Myocardial Contraction
Physical Exertion*
Technetium / diagnostic use
Time Factors
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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