| Effects of coronary-artery bypass on global and regional left ventricular function during exercise. | |
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MedLine Citation:
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PMID: 306578 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To determine the effect of coronary revascularization on exercise-induced abnormalities of left ventricular-ejection fraction and regional contraction, we obtained electrocardiograph-gated 99mTc radionuclide cineangiograms before and after operation in 23 consecutive patients. At rest, their average ejection fraction remained unchanged: 51 +/- 3 versus 54 +/- 4 per cent (+/- S.E.M.). However, 17 of the patients showed improvement of ejection fraction during postoperative exercise (increase of 51 per cent). The remaining six patients had no change or a decreased ejection fraction during exercise. All patients with improved ejection fractions during exercise were symptomatically improved. No improvement of regional function occurred at rest, but improvement did occur in regions of exercise-induced dysfunction. Although coronary revascularization has little effect on left ventricular function at rest, the ejection fraction during exercise and exercise-induced wall-motion abnormalities improve in most patients who experience symptomatic improvement. |
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Authors:
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K M Kent; J S Borer; M V Green; S L Bacharach; C L McIntosh; D M Conkle; S E Epstein |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The New England journal of medicine Volume: 298 ISSN: 0028-4793 ISO Abbreviation: N. Engl. J. Med. Publication Date: 1978 Jun |
Date Detail:
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Created Date: 1978-07-24 Completed Date: 1978-07-24 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0255562 Medline TA: N Engl J Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1434-9 Citation Subset: AIM; IM; S |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Angina Pectoris / surgery Blood Pressure Cardiac Output Cineangiography Coronary Angiography Coronary Artery Bypass* Coronary Disease / radionuclide imaging Coronary Vessels / radionuclide imaging Electrocardiography Female Heart / physiology* Heart Rate Humans Male Middle Aged Myocardial Contraction Physical Exertion* Technetium / diagnostic use Time Factors |
| Chemical | |
Reg. No./Substance:
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7440-26-8/Technetium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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