| Effects of corn gluten hydrolyzates, branched chain amino acids, and leucine on body weight reduction in obese rats induced by a high fat diet. | |
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MedLine Citation:
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PMID: 20461198 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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In this study, we compared corn gluten hydrolyzates, BCAAs, and leucine for their effects on body weight reduction in high fat-induced obese rats in order to determine the major active components in the corn gluten hydrolyzates. After obesity was induced for 13 weeks with high fat diet, the overweight-induced SD rats (n = 64) were stratified according to body weight, randomly blocked into eight treatments, and raised for 8 weeks. Four groups were changed to a normal diet and the other groups remained on the high fat diet. Each of the groups within both diets was fed either casein, corn gluten hydrolyzates, leucine, or branched chain amino acids, respectively. Daily food intake, body weight gain, and food efficiency ratio were significantly lower in the corn gluten hydrolyzate groups compared to the other groups, regardless of the high fat diet or normal fat diet. The rats fed the corn gluten hydrolyzates diet had the lowest perirenal fat pad weights whereas muscle weight was significantly increased in the corn gluten hydrolyzates groups. Plasma triglyceride, hepatic total lipid, and total cholesterol contents were significantly reduced in the corn gluten hydrolyzates groups. Other lipid profile measurements were not significantly changed. Plasma triglyceride and hepatic total lipid were also significantly reduced in the BCAA and leucine groups. Leptin levels were significantly lower and adiponectin was significantly higher in the corn gluten hydrolyzates groups. Fasting blood glucose, insulin, C-peptide, and HOMA-IR levels were also significantly reduced in the corn gluten hydrozylates groups, regardless of fat level. |
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Authors:
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Ha Yoon Bong; Ji Yeon Kim; Hye In Jeong; Min Sun Moon; Joohee Kim; Oran Kwon |
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Publication Detail:
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Type: Journal Article Date: 2010-04-28 |
Journal Detail:
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Title: Nutrition research and practice Volume: 4 ISSN: 2005-6168 ISO Abbreviation: Nutr Res Pract Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-05-12 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101311052 Medline TA: Nutr Res Pract Country: Korea (South) |
Other Details:
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Languages: eng Pagination: 106-13 Citation Subset: - |
Affiliation:
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Department of Nutritional Science and Food Management, Ewha Woman's University, 11-1 Daehyeon-dong, Seodeamun-gu, Seoul 120-750, Korea. |
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