Document Detail

Effects of continuous vs. interval exercise training on blood pressure and arterial stiffness in treated hypertension.
MedLine Citation:
PMID:  20379194     Owner:  NLM     Status:  MEDLINE    
Exercise is an effective intervention for treating hypertension and arterial stiffness, but little is known about which exercise modality is the most effective in reducing arterial stiffness and blood pressure in hypertensive subjects. Our purpose was to evaluate the effect of continuous vs. interval exercise training on arterial stiffness and blood pressure in hypertensive patients. Sixty-five patients with hypertension were randomized to 16 weeks of continuous exercise training (n=26), interval training (n=26) or a sedentary routine (n=13). The training was conducted in two 40-min sessions a week. Assessment of arterial stiffness by carotid-femoral pulse wave velocity (PWV) measurement and 24-h ambulatory blood pressure monitoring (ABPM) were performed before and after the 16 weeks of training. At the end of the study, ABPM blood pressure had declined significantly only in the subjects with higher basal values and was independent of training modality. PWV had declined significantly only after interval training from 9.44+/-0.91 to 8.90+/-0.96 m s(-1), P=0.009 (continuous from 10.15+/-1.66 to 9.98+/-1.81 m s(-1), P=ns; control from 10.23+/-1.82 to 10.53+/-1.97 m s(-1), P=ns). Continuous and interval exercise training were beneficial for blood pressure control, but only interval training reduced arterial stiffness in treated hypertensive subjects.
Guilherme Veiga Guimarães; Emmanuel Gomes Ciolac; Vitor Oliveira Carvalho; Veridiana Moraes D'Avila; Luiz Aparecido Bortolotto; Edimar Alcides Bocchi
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2010-04-09
Journal Detail:
Title:  Hypertension research : official journal of the Japanese Society of Hypertension     Volume:  33     ISSN:  1348-4214     ISO Abbreviation:  Hypertens. Res.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-04     Completed Date:  2010-09-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9307690     Medline TA:  Hypertens Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  627-32     Citation Subset:  IM    
Faculdade de Medicina, Heart Institute InCor, Hospital das Clínicas, Universidade de São Paulo, São Paulo, Brazil.
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MeSH Terms
Adrenergic beta-Antagonists / therapeutic use
Angiotensin-Converting Enzyme Inhibitors / therapeutic use
Blood Pressure / physiology*
Blood Pressure Monitoring, Ambulatory
Calcium Channel Blockers / therapeutic use
Carotid Arteries / physiopathology
Diuretics / therapeutic use
Exercise Therapy / methods*
Femoral Artery / physiopathology
Hypertension / drug therapy,  physiopathology*,  therapy*
Middle Aged
Waist Circumference
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Angiotensin-Converting Enzyme Inhibitors; 0/Calcium Channel Blockers; 0/Diuretics
Comment In:
Hypertens Res. 2010 Jun;33(6):544-5   [PMID:  20431596 ]

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