Document Detail


Effects of compressed unsaturated hydrocarbon gases on yeast growth.
MedLine Citation:
PMID:  20233377     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effect of compressed unsaturated hydrocarbon gases on the growth of the yeast Saccharomyces cerevisiae was investigated by microcalorimetry. The growth thermograms showed that unsaturated hydrocarbon gases inhibited yeast growth. As an approach to determining the comparative toxicity of unsaturated hydrocarbon gases, we determined the 50% inhibitory pressure (IP(50)) and the minimum inhibitory pressure (MIP). On the basis of the IP(50) and MIP values, the inhibitory potency of the gases increased in the order ethylene < propylene < 1-butene. Additionally, scanning electron microscopy showed that cells treated with unsaturated hydrocarbon gases were damaged, including invagination of the cell surface.
Authors:
Satoshi Kawachi; Toshiaki Arao; Yoshihisa Suzuki; Katsuhiro Tamura
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of the New York Academy of Sciences     Volume:  1189     ISSN:  1749-6632     ISO Abbreviation:  Ann. N. Y. Acad. Sci.     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-03-17     Completed Date:  2010-04-02     Revised Date:  2010-10-19    
Medline Journal Info:
Nlm Unique ID:  7506858     Medline TA:  Ann N Y Acad Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  121-6     Citation Subset:  IM    
Affiliation:
Department of Life System, Institute of Technology and Science, University of Tokushima, Japan.
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MeSH Terms
Descriptor/Qualifier:
Air Pollutants / chemistry,  toxicity*
Alkenes / chemistry,  toxicity
Biotechnology
Calorimetry
Cell Membrane / drug effects,  ultrastructure
Ethylenes / chemistry,  toxicity
Gases
Hydrocarbons / chemistry,  toxicity*
Hydrophobicity
Hydrostatic Pressure
Microscopy, Electron, Scanning
Saccharomyces cerevisiae / drug effects*,  growth & development*,  ultrastructure
Chemical
Reg. No./Substance:
0/Air Pollutants; 0/Alkenes; 0/Ethylenes; 0/Gases; 0/Hydrocarbons; 106-98-9/1-butene; 115-07-1/propylene; 74-85-1/ethylene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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