Document Detail


Effects of coasting on the outcome of intracytoplasmic sperm injection-embryo transfer cycles.
MedLine Citation:
PMID:  15281999     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To determine the effects of 'coasting' on the outcome of controlled ovarian hyperstimulation (COH) and intracytoplasmic sperm injection-embryo transfer (ICSI-ET). DESIGN: Retrospective study. SETTING: IVF Centre, Ozel Ege Tup Bebek Merkezi, Izmir, Turkey. SAMPLE: Twenty-six coasted and 52 non-coasted COH and ICSI-ET patients were enrolled in this retrospective study. METHODS: Coasted patients were enrolled consecutively during the study period, and two non-coasted controls were selected from our database for each coasted patient. Coasting was decided when serum oestradiol level was > or = 4000 pg/mL. Groups were compared using chi2 and Mann-Whitney U-tests for statistical analysis. MAIN OUTCOME MEASURES: Number of oocytes collected, metaphase II (MII) oocytes and cleaving embryos, the fertilisation rate and clinical pregnancy rate were the main outcome measures. RESULTS: Number of oocytes collected, number of MII oocytes, number of cleaving embryos, fertilisation rate and clinical pregnancy rate for the coasted and non-coasted groups were 15.5 +/- 5.2 and 14.0 +/- 7.1, 9.7 +/- 4.8 and 9.3 +/- 3.9, 6.8 +/- 3.9 and 5.8 +/- 3.1, 0.85 +/- 0.18 and 0.78 +/- 0.18, 13/26 and 24/52, respectively; these differences were not statistically significant. None of the patients in the coasted group were hospitalised for signs or findings of severe ovarian hyperstimulation syndrome. CONCLUSIONS: Coasting does not adversely affect the number and the function of mature oocytes and the clinical pregnancy rate.
Authors:
Erdal Aktan; Kaan Bozkurt; Dilek Ozer; Sait Yucebilgin; Nedim Karadadas; Onur Bilgin
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  The Australian & New Zealand journal of obstetrics & gynaecology     Volume:  44     ISSN:  0004-8666     ISO Abbreviation:  Aust N Z J Obstet Gynaecol     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-07-29     Completed Date:  2005-04-18     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0001027     Medline TA:  Aust N Z J Obstet Gynaecol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  298-301     Citation Subset:  IM    
Affiliation:
IVF Department, Ozel Ege Tup Bebek Merkezi, Izmir, Turkey. sebnem.aktan@deu.edu.tr
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MeSH Terms
Descriptor/Qualifier:
Embryo Transfer*
Female
Hormones / metabolism,  therapeutic use
Humans
Oocytes / metabolism
Ovarian Hyperstimulation Syndrome / therapy*
Pregnancy
Retrospective Studies
Sperm Injections, Intracytoplasmic / methods*
Treatment Outcome
Turkey
Chemical
Reg. No./Substance:
0/Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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