Document Detail


Effects of chronic renal failure and hemodialysis on hormonal evaluation of pregnancy.
MedLine Citation:
PMID:  3369475     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Different hormonal parameters are studied in a pregnant woman with chronic renal failure undergoing hemodialysis. Serum concentrations of human chorionic gonadotropin, progesterone, 17-hydroxyprogesterone, alpha-fetoprotein, human placental lactogen were all higher than the normal range. This is probably related to a decreased metabolic clearance rate of these hormones. Dehydroepiandrosterone sulfate (DHEAS), which is low before pregnancy and during the first week of gestation, tends to increase later. Serum estradiol is lower than the normal range. This decrease probably results from the low concentration of DHEAS available to placental aromatization. Finally, pregnancy-specific beta 1-glycoprotein concentration follows the normal range and may be considered as the most reliable parameters to evaluate the fetoplacental well-being in these high-risk pregnancies.
Authors:
C J Hubinont; M Goldman; J L Vanherweghem; J Schwers
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of nephrology     Volume:  8     ISSN:  0250-8095     ISO Abbreviation:  Am. J. Nephrol.     Publication Date:  1988  
Date Detail:
Created Date:  1988-06-14     Completed Date:  1988-06-14     Revised Date:  2007-02-14    
Medline Journal Info:
Nlm Unique ID:  8109361     Medline TA:  Am J Nephrol     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  57-61     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Erasme Hospital, Brussels Free University, Belgium.
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MeSH Terms
Descriptor/Qualifier:
Adult
Chorionic Gonadotropin / blood
Estradiol / blood
Female
Hormones / blood*
Humans
Kidney Failure, Chronic / blood*,  therapy
Pregnancy
Pregnancy Complications / blood*,  therapy
Progesterone / blood
Renal Dialysis*
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Hormones; 50-28-2/Estradiol; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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