Document Detail


Effects of cholecystectomy on the changes of motility of Beagle dogs' sphincter of Oddi.
MedLine Citation:
PMID:  24760024     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
PURPOSE: To observe the effect of cholecystectomy on the changes of motion pattern of Beagle dogs' sphincter of Oddi (SO), and investigate the modulatory role of nitric oxide (NO) and cholecystokinin (CCK) in the regulation of SO.
METHODS: Pressure of common bile duct, SO motility, response to bolus injections of cholecystokinin (CCK, 20 ng/kg and 100 ng/kg), basal pressure (BP) and phasic contraction amplitude (PCA) were measured respectively by manometry in six Beagle dogs before and after cholecystectomy.
RESULTS: After cholecystectomy, the pressure and diameter of common bile ducts (CBD) was significantly increased (p<0.01); BP and phasic contraction frequency (PCF) were also increased, however, no significant differences were found between the two groups; the SO motilities was not significantly changed. The relaxation responded to physiological dose of CCK (20ng/kg) was decreased, while bolus-dose of CCK (100ng/kg) induced rapid contractions and decreased PCA after cholecystectomy. The regulation pattern of SO pressure modulated by NO and its inhibitor had changed after cholecystectomy.
CONCLUSION: After cholecystectomy in Beagle dogs, no obviously change of motion pattern of SO was observed through self-compensation, but these compensations may lead to some changes of regulation pattern of CCK and NO on SO.
Authors:
Fu Li; Xi-Wen Zhang; Ke-Wei Li; Jun Ding; Gui-Yang Wang
Related Documents :
9505774 - Effect of positive end-expiratory pressure on the incidence of venous air embolism and ...
8839594 - High-inflation pressure and positive end-expiratory pressure. injurious to the lung? yes.
4565164 - Ventilation with end-expiratory pressure in acute lung disease.
11964584 - Sigh improves gas exchange and lung volume in patients with acute respiratory distress ...
793284 - Effect of intermittent positive pressure ventilation on cardiac systolic time intervals.
21147054 - Associations between sociocultural pressures to be thin, body distress, and eating diso...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta cirúrgica brasileira / Sociedade Brasileira para Desenvolvimento Pesquisa em Cirurgia     Volume:  29     ISSN:  1678-2674     ISO Abbreviation:  Acta Cir Bras     Publication Date:  2014 Apr 
Date Detail:
Created Date:  2014-04-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9103983     Medline TA:  Acta Cir Bras     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  237-44     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Spongy film of cellulosic polysaccharide as a dressing for aphthous stomatitis treatment in rabbits.
Next Document:  Analgesic comparison of systemic lidocaine, morphine or lidocaine plus morphine infusion in dogs und...