Document Detail

Effects of central administration of insulin in normal and VMH (ventromedial hypothalamus) lesioned rats on food intake.
MedLine Citation:
PMID:  2695463     Owner:  NLM     Status:  MEDLINE    
Central effects of insulin on 20 min. food intake were studied in rats. Insulin administration in the lateral ventricular cerebrospinal fluid (CSF) did not alter food intake in the intact or lesioned ventromedial hypothalamus (VMH) rats. Whereas, after insulin injection in VMH there was a decrease in food intake. In VMH lesioned rats, subcutaneous injection of insulin increased food intake.
D P Thombre; S Bharathi; N Krishnamurthy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of physiology and pharmacology     Volume:  33     ISSN:  0019-5499     ISO Abbreviation:  Indian J. Physiol. Pharmacol.     Publication Date:    1989 Oct-Dec
Date Detail:
Created Date:  1990-03-19     Completed Date:  1990-03-19     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0374707     Medline TA:  Indian J Physiol Pharmacol     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  207-10     Citation Subset:  IM    
Department of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry.
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MeSH Terms
Body Weight / drug effects
Eating / physiology*
Injections, Intraventricular
Insulin / administration & dosage,  pharmacology*
Ventromedial Hypothalamic Nucleus / physiology*
Reg. No./Substance:

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