Document Detail

Effects of calcium on the erosive potential of acidic candies in saliva.
MedLine Citation:
PMID:  17167262     Owner:  NLM     Status:  MEDLINE    
Theoretical calculations have shown that acidic candies may be potentially erosive upon consumption. However, little is known about the protective effect of adding calcium to potentially erosive candies and about the protective effects of saliva that cannot be fully accounted for by theoretical calculations. Therefore, the aims of this study were to (1) determine the erosive potential of acidic candies with and without calcium and (2) to determine differences between theoretically calculated erosive potential and actual erosive potential in saliva. Twenty healthy test persons sucked acidic candy with and without calcium while their whole saliva was collected into a closed system at different times: baseline, candy-stimulated, and post-stimulated. The erosive potential of the candy was evaluated from candy-induced changes in saliva degree of saturation with respect to hydroxyapatite (HAp) and directly by dissolution of HAp crystals in candy-stimulated saliva. The results showed that similar salivary stimulation was obtained with both candies. The modified candy released more than 13 mmol/l of calcium into saliva, resulting in a lower critical pH, and considerably lower erosive potential than the control (p < 0.001). Although a significant correlation was obtained between theoretical calculation of DS(HAp) and dissolution of HAp crystals (r(s) = 0.65; p < 0.001), many samples obtained by sucking modified candy showed no signs of HAp dissolution in spite of being undersaturated. We conclude that saturation levels and critical pH may not fully reflect when dental erosion is expected to occur in saliva and that calcium addition reduces the erosive potential of acidic candies.
T Jensdottir; B Nauntofte; C Buchwald; A Bardow
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Caries research     Volume:  41     ISSN:  0008-6568     ISO Abbreviation:  Caries Res.     Publication Date:  2007  
Date Detail:
Created Date:  2006-12-14     Completed Date:  2007-04-02     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0103374     Medline TA:  Caries Res     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  68-73     Citation Subset:  D; IM    
Department of Oral Medicine, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark.
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MeSH Terms
Calcium / pharmacology*
Candy / adverse effects*
Cariostatic Agents / pharmacology*
Durapatite / analysis
Hydrogen-Ion Concentration / drug effects
Regression Analysis
Saliva / chemistry*,  drug effects
Salivation / physiology
Statistics as Topic
Statistics, Nonparametric
Tooth Erosion / chemically induced*,  prevention & control
Reg. No./Substance:
0/Cariostatic Agents; 1306-06-5/Durapatite; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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