Document Detail


Effects of caffeine and caffeine-associated stimuli on the human startle eyeblink reflex.
MedLine Citation:
PMID:  9443534     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An experiment was performed (n = 19) that investigated the effect of caffeine and expectancy of caffeine on the eyeblink component of the startle reflex. Nineteen habitual caffeine users received caffeinated coffee, caffeinated juice, decaffeinated coffee, or decaffeinated juice in four sessions spaced 1 week apart. Twenty-five to 30 min after ingestion of the liquid, 30 acoustic startle stimuli were presented. The results showed that caffeine increased startle eyeblink amplitude. Startle reflex onset latency was significantly longer in the decaffeinated coffee condition than in the other three conditions. This may have been due to the activation of a compensatory slowing of the reflex by the anticipation of caffeine, a slowing that was then overridden by caffeine speeding the response.
Authors:
S E Andrews; T D Blumenthal; M A Flaten
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Pharmacology, biochemistry, and behavior     Volume:  59     ISSN:  0091-3057     ISO Abbreviation:  Pharmacol. Biochem. Behav.     Publication Date:  1998 Jan 
Date Detail:
Created Date:  1998-03-09     Completed Date:  1998-03-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0367050     Medline TA:  Pharmacol Biochem Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  39-44     Citation Subset:  IM    
Affiliation:
Wake Forest University, Winston-Salem, NC 27109, USA.
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MeSH Terms
Descriptor/Qualifier:
Acoustic Stimulation
Adult
Blinking / drug effects*
Caffeine / pharmacology*
Cues*
Female
Humans
Male
Reaction Time / drug effects
Startle Reaction / drug effects*
Chemical
Reg. No./Substance:
58-08-2/Caffeine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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