Document Detail

Effects of buffered 2.3%, buffered 0.9%, and non-buffered 0.9% irrigation solutions on nasal mucosa after septoplasty.
MedLine Citation:
PMID:  18802718     Owner:  NLM     Status:  MEDLINE    
A prospective randomized study was designed to compare the effect of different irrigation solutions on mucociliary clearance and nasal patency and to compare the limitations of the used solutions, such as nasal burning by a visual analog scale. Forty-five patients who underwent septoplasty were divided into three groups postoperatively. Each group was administered with 2.3% buffered hypertonic seawater, buffered isotonic saline solution and non-buffered isotonic saline, respectively, as irrigation fluid. Saccharine test and acoustic rhinometer were used to determine mucociliary activity and nasal patency. Patients were asked about the burning sensation using a 10-cm visual analog scale. There was no significant difference in saccharine clearance time (SCT) on the 5th postoperative day between the three groups (P = 0.07). On the 20th day, there was a significant difference in SCT between the hypertonic buffered seawater group and non-buffered isotonic saline (P = 0.003). Buffered hypertonic seawater improved nasal airway patency more than the buffered isotonic saline (P = 0.004). Buffered hypertonic solutions used after endonasal surgery have been advantageous for both mucociliary clearance and postoperative decongestion.
Nilda Süslü; Münir Demir Bajin; Ahmet Emre Süslü; Oğuz Oğretmenoğlu
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2008-09-18
Journal Detail:
Title:  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery     Volume:  266     ISSN:  1434-4726     ISO Abbreviation:  Eur Arch Otorhinolaryngol     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-03-24     Completed Date:  2009-07-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9002937     Medline TA:  Eur Arch Otorhinolaryngol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  685-9     Citation Subset:  IM    
Department of Otorhinolaryngology, Faculty of Medicine, Hacettepe University, 06100, Sihhiye, Ankara, Turkey.
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MeSH Terms
Administration, Intranasal
Irrigation / methods*
Mucociliary Clearance / drug effects
Nasal Mucosa / drug effects*,  surgery*
Nasal Obstruction / diagnosis,  drug therapy*
Nasal Septum / drug effects*,  surgery*
Postoperative Period
Prospective Studies
Rhinometry, Acoustic
Saline Solution, Hypertonic / administration & dosage*
Sodium Chloride / administration & dosage*
Reg. No./Substance:
0/Buffers; 0/Saline Solution, Hypertonic; 7647-14-5/Sodium Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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