Document Detail

Effects of breathing warm humidified air on bronchoconstriction induced by body cooling and by inhalation of methacholine.
MedLine Citation:
PMID:  421517     Owner:  NLM     Status:  MEDLINE    
The effect of breathing warm humidified air upon bronchoconstriction induced with body cooling or inhalation of methacholine was studied in two groups of eight asthmatic subjects. One group had the body cooled using one-minute exposures, first to a cold shower at 15 degrees C and then to a current of wind. The other group received methacholine by inhalation until a decrease of 20 percent or more occurred in the forced expiratory volume in one second. Both groups of asthmatic subjects were tested when breathing room air and warm humidified air. Pulmonary functions were assessed before and after cooling of the body and during inhalation of methacholine. Breathing warm humidified air substantially reduced bronchoconstriction induced by body cooling, but not that induced by inhalation of methacholine. Thus, bronchoconstriction induced by cooling of the body appears to be related to cooling of the airways, which may be compensated by breathing warm humidified air.
D J Horton; W Y Chen
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Chest     Volume:  75     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1979 Jan 
Date Detail:
Created Date:  1979-05-16     Completed Date:  1979-05-16     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  24-8     Citation Subset:  AIM; IM    
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MeSH Terms
Airway Resistance
Asthma / etiology,  physiopathology,  therapy*
Cold Temperature
Forced Expiratory Volume
Hot Temperature*
Maximal Midexpiratory Flow Rate
Methacholine Compounds* / administration & dosage
Respiratory Therapy*
Skin Temperature
Reg. No./Substance:
0/Methacholine Compounds

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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