| Effects of bile reflux and intragastric microflora changes on lesions of remnant gastric mucosa after gastric operation. | |
MedLine Citation:
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PMID: 15133869 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: To investigate the effects of bile reflux and intragastric microflora changes on lesions of remnant gastric mucosa after gastric operation. METHODS: Concentration of bile acid and total bacterial counts (TBC) in gastric juice were measured in 49 patients with peptic ulcer before and after gastrectomy. One year after the operation, sample of gastric mucosa taken from all the patients were used for histological examination. RESULTS: The concentration of gastric bile acid was significantly increased in group B-I, or B-II and SV+A than that in group HSV (P<0.05-0.01). The abnormal histological changes in the remnant gastric mucosa were more common in the first 2 groups than in the last group. CONCLUSION: The type of gastrectomy can affect bile reflux. The abnormal histological changes in the remnant gastric mucosa are closely related to the elevation of bile acid concentration and increase of TBC in gastric juice. HSV can effectively prevent bile reflux and keep the gastric physiological functions stable. |
Authors:
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Chao Zhang; Zhan-Kui Liu; Pei-Wu Yu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 10 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2004 May |
Date Detail:
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Created Date: 2004-05-10 Completed Date: 2005-02-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 1537-9 Citation Subset: IM |
Affiliation:
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Department of General Surgery, Southwest Hospital, Third Military Medical University, Gaotan Yan, Chongqing 400038, China. meizhang6688@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bile Acids and Salts / analysis Bile Reflux* Female Gastrectomy* / adverse effects Gastric Juice* / chemistry, microbiology Gastric Mucosa* / microbiology, pathology, surgery Humans Male Postgastrectomy Syndromes Stomach Ulcer / surgery |
| Chemical | |
Reg. No./Substance:
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0/Bile Acids and Salts |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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