| Effects of bacterial lipopolysaccharides (LPS) on leukocytes and platelets. Recent views on the pathophysiological role of LPS in the host. | |
| | |
MedLine Citation:
|
PMID: 6765397 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Some effects of bacterial endotoxin on leukocytes and platelets are reviewed. The release of two mediators, Leukocyte Inhibiting Factor (LIF) and Tissue Factor (TF) from human mononuclear cells are described. These factors may play either beneficial effects (LIF) or noxious activities (TF liberation in certain pathological conditions). Regarding the activities of LPS on platelets the AA. report some personal data about the electrokinetic modification of platelets due to endotoxin. This LPS effect can be performed directly or via a lymphokine release, Platelet Slowing Factor (PSF). In the light of all the mentioned considerations, a scheme of interaction LPS/platelets is suggested. |
| | |
Authors:
|
E Jirillo; G Miragliotta; D Fumarola |
Related Documents
:
|
8528547 - Protective effect of no on gastric lesions and inhibition of expression of gastric indu... 8719347 - Alterations in cranial morphogenesis in the lp mutant mouse. 8607107 - Recombinant human soluble thrombomodulin reduces endotoxin-induced pulmonary vascular i... 7831357 - A case for an endotoxic conformation. 22472297 - Immature platelet fraction as marker for platelet recovery after stem cell transplantat... 11012197 - Opportunities for the use of thrombopoietic growth factors. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Bollettino dell'Istituto sieroterapico milanese Volume: 61 ISSN: 0021-2547 ISO Abbreviation: Boll Ist Sieroter Milan Publication Date: 1982 |
Date Detail:
|
Created Date: 1985-09-25 Completed Date: 1985-09-25 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 17720040R Medline TA: Boll Ist Sieroter Milan Country: ITALY |
Other Details:
|
Languages: eng Pagination: 285-93 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Blood Coagulation Disorders / etiology Blood Platelets / drug effects*, physiology Humans Infant, Newborn Leukocytes / drug effects*, immunology Lipopolysaccharides / pharmacology* Lymphokines / analysis, secretion Mice Rabbits Rats T-Lymphocytes / immunology Thromboplastin / physiology |
| Chemical | |
Reg. No./Substance:
|
0/Lipopolysaccharides; 0/Lymphokines; 0/leukocyte inhibitory factor; 9035-58-9/Thromboplastin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Subconjunctival emphysema as a complication of PEEP.
Next Document: Relation between viral antigens in hepatic tissue detected by immunofluorescence and serological mar...