Document Detail

Effects of atypical antipsychotics on weight and serum lipid levels.
MedLine Citation:
PMID:  11806486     Owner:  NLM     Status:  MEDLINE    
Psychiatrists have become particularly concerned about health issues in patients with schizophrenia because of emerging data that link some of the newer atypical antipsychotics with both significant weight gain and increases in serum triglyceride levels. Excessive weight gain during antipsychotic therapy has an adverse effect on health and medication compliance, while hyperlipidemia presents an additional cardiovascular risk factor in patients with schizophrenia who typically smoke, are inactive, and possess poor dietary habits. An understanding of appropriate monitoring for metabolic adverse effects is important for those who prescribe atypical antipsychotics, as is a working knowledge of behavioral and pharmacologic treatments for weight gain and hyperlipidemia.
J M Meyer
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of clinical psychiatry     Volume:  62 Suppl 27     ISSN:  0160-6689     ISO Abbreviation:  J Clin Psychiatry     Publication Date:  2001  
Date Detail:
Created Date:  2002-01-24     Completed Date:  2002-02-07     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7801243     Medline TA:  J Clin Psychiatry     Country:  United States    
Other Details:
Languages:  eng     Pagination:  27-34; discussion 40-1     Citation Subset:  IM    
San Diego Veterans Affairs Medical Center and the Department of Psychiatry, University of California, 92161, USA.
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MeSH Terms
Antipsychotic Agents / adverse effects*,  therapeutic use
Body Weight / drug effects*
Drug Monitoring
Hypertriglyceridemia / blood,  chemically induced
Lipids / blood*
Obesity / chemically induced
Risk Factors
Schizophrenia / blood,  drug therapy*
Reg. No./Substance:
0/Antipsychotic Agents; 0/Lipids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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