Document Detail


Effects of artificial food colorings in children with hyperactive symptoms. A critical review and results of a controlled study.
MedLine Citation:
PMID:  7247635     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The "Feingold diet," which eliminates artificial food colorings, has been claimed to be beneficial to hyperactive children. Previous studies have yielded equivocal results. We sought to maximize the likelihood of demonstrating behavioral effects of artificial food colorings by (1) studying only children who were already on the Feingold diet and who were reported by their parents to respond markedly to artificial food colorings, (2) attempting to exclude placebo responders, and (3) administering high dosages of coloring. The design was a double-blind crossover with randomized; 11 children maintained on the Feingold diet were challenged with food coloring and placebo (one each week). Evaluations by parents, teachers, and psychiatrists and psychological testing yielded no evidence of a food coloring effect.
Authors:
J A Mattes; R Gittelman
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of general psychiatry     Volume:  38     ISSN:  0003-990X     ISO Abbreviation:  Arch. Gen. Psychiatry     Publication Date:  1981 Jun 
Date Detail:
Created Date:  1981-08-10     Completed Date:  1981-08-10     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372435     Medline TA:  Arch Gen Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  714-8     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Attention / drug effects
Attention Deficit Disorder with Hyperactivity / chemically induced*,  diet therapy
Child
Child, Preschool
Dose-Response Relationship, Drug
Female
Food Coloring Agents / adverse effects*
Humans
Male
Motor Activity / drug effects
Grant Support
ID/Acronym/Agency:
MH 18579/MH/NIMH NIH HHS; MH 31849/MH/NIMH NIH HHS; MH 32025-01/MH/NIMH NIH HHS
Chemical
Reg. No./Substance:
0/Food Coloring Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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