| Effects of artificial food colorings in children with hyperactive symptoms. A critical review and results of a controlled study. | |
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MedLine Citation:
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PMID: 7247635 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The "Feingold diet," which eliminates artificial food colorings, has been claimed to be beneficial to hyperactive children. Previous studies have yielded equivocal results. We sought to maximize the likelihood of demonstrating behavioral effects of artificial food colorings by (1) studying only children who were already on the Feingold diet and who were reported by their parents to respond markedly to artificial food colorings, (2) attempting to exclude placebo responders, and (3) administering high dosages of coloring. The design was a double-blind crossover with randomized; 11 children maintained on the Feingold diet were challenged with food coloring and placebo (one each week). Evaluations by parents, teachers, and psychiatrists and psychological testing yielded no evidence of a food coloring effect. |
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Authors:
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J A Mattes; R Gittelman |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Archives of general psychiatry Volume: 38 ISSN: 0003-990X ISO Abbreviation: Arch. Gen. Psychiatry Publication Date: 1981 Jun |
Date Detail:
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Created Date: 1981-08-10 Completed Date: 1981-08-10 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0372435 Medline TA: Arch Gen Psychiatry Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 714-8 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Attention / drug effects Attention Deficit Disorder with Hyperactivity / chemically induced*, diet therapy Child Child, Preschool Dose-Response Relationship, Drug Female Food Coloring Agents / adverse effects* Humans Male Motor Activity / drug effects |
| Grant Support | |
ID/Acronym/Agency:
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MH 18579/MH/NIMH NIH HHS; MH 31849/MH/NIMH NIH HHS; MH 32025-01/MH/NIMH NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Food Coloring Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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