Document Detail

Effects of the application of Aloe vera (L.) and microcurrent on the healing of wounds surgically induced in Wistar rats.
MedLine Citation:
PMID:  19377785     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To investigate the effects of topical application of an Aloe vera gel combined or not with microcurrent application on the healing of skin wounds surgically induced in Wistar rats. METHODS: The animals were randomly divided into the following groups: control group, animals topically treated with Aloe vera, animals treated with a microcurrent, and animals receiving topical application of Aloe vera combined with microcurrent application. RESULTS: The results indicated differences in wound healing between the various treatments when compared to the control group. Tissue hyperplasia was lower in the control group compared to the other treated groups. Accelerated wound healing was observed in the group treated with Aloe vera compared to control. Animals submitted to microcurrent application only and the group treated with microcurrent plus Aloe vera presented an earlier onset of the proliferative phase compared to the control group and animals treated with Aloe vera gel alone. Morphometric data confirmed the structural findings. CONCLUSION: Simultaneous application of Aloe vera gel and microcurrent is an excellent choice for the treatment of open wounds thus indicating a synergistic action of these two applications.
Fernanda Aparecida Sampaio Mendonça; José Roberto Passarini Junior; Marcelo Augusto Marretto Esquisatto; Josué Sampaio Mendonça; Cristina Cruz Franchini; Glaucia Maria Tech dos Santos
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta cirúrgica brasileira / Sociedade Brasileira para Desenvolvimento Pesquisa em Cirurgia     Volume:  24     ISSN:  1678-2674     ISO Abbreviation:  Acta Cir Bras     Publication Date:    2009 Mar-Apr
Date Detail:
Created Date:  2009-04-20     Completed Date:  2009-11-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9103983     Medline TA:  Acta Cir Bras     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  150-5     Citation Subset:  IM    
Physiology Division, Herminio Ometto University Center, UNIARARAS, Araras-SP, Brazil.
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MeSH Terms
Administration, Topical
Analysis of Variance
Disease Models, Animal
Drug Evaluation, Preclinical
Electric Stimulation Therapy / methods*
Plant Extracts / therapeutic use*
Rats, Wistar
Wound Healing* / drug effects,  physiology
Reg. No./Substance:
0/Plant Extracts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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