Document Detail

Effects of an antihypertensive medication on functional capacity under simulated flight-typical stress-conditions.
MedLine Citation:
PMID:  10477504     Owner:  NLM     Status:  MEDLINE    
A model to investigate the functional capacity (psychomental performance) under stressful conditions was developed. Twenty eight patients with mild hypertension receiving Nitrendipine (20 mg) for 30 days were tested under hypoxic (16% oxygen) and/or orthostatic (-30 mmHg lower body negative pressure) conditions using a subset of the AGARD battery. The main effect was a decreasing performance of the grammatical reasoning task (GRT) under hypoxia or the combination of hypoxia and orthostasis. A simultaneous application of stressors while performing psychometric test batteries may be useful to reveal pharmaceutical influences on human performance and may help to recommend the use of drugs in occupational medicine.
G Wolfram; C Drummer; R Helbig; C Hesse; R Klan; W D Sittner; F Baisch
Related Documents :
9247764 - Effect of central endogenous angiotensin ii on sympathetic activation induced by hypoxia.
3800034 - Pulmonary hemodynamic response to dopamine and dobutamine in hyperoxic and in hypoxic d...
2366754 - The metabolic effect of carbon monoxide on the heart.
2085704 - Activities of endothelin-1 in the vascular network of the rabbit ear: a microangiograph...
7967764 - Hypertension in pediatric patients: current issues.
16429644 - A patient with high normal blood pressure--should we treat?
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  European journal of medical research     Volume:  4     ISSN:  0949-2321     ISO Abbreviation:  Eur. J. Med. Res.     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-11-04     Completed Date:  1999-11-04     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9517857     Medline TA:  Eur J Med Res     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  379-81     Citation Subset:  IM; S    
Institut für Flugmedizin der RWTH Aachen, Pauwelsstr. 30, 52057 Aachen, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aerospace Medicine
Anoxia / physiopathology*
Antihypertensive Agents / administration & dosage*
Nitrendipine / administration & dosage*
Occupational Diseases / drug therapy*,  physiopathology
Stress, Physiological / physiopathology*
Reg. No./Substance:
0/Antihypertensive Agents; 39562-70-4/Nitrendipine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Lung function requirements in flying duty the problem of bronchial hyperresponsiveness in military a...
Next Document:  New refractive surgery procedures in ophthalmology and the influence on Pilot's fitness for flying.