Document Detail


Effects of anger on left ventricular ejection fraction in coronary artery disease.
MedLine Citation:
PMID:  1632389     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study examined the comparative potency of several psychological stressors and exercise in eliciting myocardial ischemia as measured by left ventricular (LV) ejection fraction (EF) changes using radionuclide ventriculography. Twenty-seven subjects underwent both exercise (bicycle) and psychological stressors (mental arithmetic, recall of an incident that elicited anger, giving a short speech defending oneself against a charge of shoplifting) during which EF, blood pressure, heart rate and ST segment were measured. Eighteen subjects had 1-vessel coronary artery disease (CAD), defined by greater than 50% diameter stenosis in 1 artery as assessed by arteriography. Nine subjects served as healthy control subjects. Anger recall reduced EF more than exercise and the other psychological stressors (overall F [3.51] = 2.87, p = .05). Respective changes in EF for the CAD patients were -5% during anger recall, +2% during exercise, 0% during mental arithmetic and 0% during the speech stressor. More patients with CAD had significant reduction in EF (greater than or equal to 7%) during anger (7 of 18) than during exercise (4 of 18). The difference in EF change between patients with CAD and healthy control subjects was significant for both anger (t25 = 2.23, p = 0.04) and exercise (t25 = 2.63, p = 0.01) stressors. In this group of patients with CAD, anger appeared to be a particularly potent psychological stressor.
Authors:
G Ironson; C B Taylor; M Boltwood; T Bartzokis; C Dennis; M Chesney; S Spitzer; G M Segall
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of cardiology     Volume:  70     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1992 Aug 
Date Detail:
Created Date:  1992-08-20     Completed Date:  1992-08-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  281-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Psychology, University of Miami, Coral Gables.
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MeSH Terms
Descriptor/Qualifier:
Anger / physiology*
Anxiety / physiopathology
Blood Pressure
Coronary Disease / physiopathology,  psychology*,  radionuclide imaging
Electrocardiography
Exercise Test
Heart Rate
Humans
Male
Middle Aged
Myocardial Contraction
Radionuclide Ventriculography
Stress, Psychological / physiopathology
Stroke Volume*
Grant Support
ID/Acronym/Agency:
MH 16744-07/MH/NIMH NIH HHS
Comments/Corrections
Comment In:
Am J Cardiol. 1993 Feb 15;71(5):500   [PMID:  8430663 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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