Document Detail

Effects of amylin on appetite regulation and memory.
MedLine Citation:
PMID:  8846398     Owner:  NLM     Status:  MEDLINE    
Amylin has been demonstrated to decrease food intake in mice and rats. Amylin is effective when delivered both peripherally and directly into the central nervous system. Amylin's effect on food intake is not aversive. Amylin may produce its effect on food intake by modulating nitric oxide synthesis. Calcitonin gene related peptide also decreases food intake after peripheral and central administration. In addition, amylin has been demonstrated to modulate memory at both peripheral and central sites.
J E Morley; J F Flood; S A Farr; H J Perry; F E Kaiser; P M Morley
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Canadian journal of physiology and pharmacology     Volume:  73     ISSN:  0008-4212     ISO Abbreviation:  Can. J. Physiol. Pharmacol.     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1996-10-23     Completed Date:  1996-10-23     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0372712     Medline TA:  Can J Physiol Pharmacol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1042-6     Citation Subset:  IM    
Education and Clinical Center, St. Louis VA Medical Center, MO, USA.
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MeSH Terms
Amyloid / pharmacology*
Anorexia / etiology
Appetite / drug effects*
Calcitonin Gene-Related Peptide / physiology
Memory / drug effects*
Reg. No./Substance:
0/Amyloid; 106602-62-4/amylin; 83652-28-2/Calcitonin Gene-Related Peptide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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