Document Detail


Effects of amyl nitrite on phasic aortocoronary bypass graft blood velocity in man.
MedLine Citation:
PMID:  300556     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
With the use of a Doppler flowmeter catheter, phasic instantaneous aortocoronary saphenous vein bypass graft blood velocity was continuously measured during the inhalation of amyl nitrite in 20 closed-chest conscious subjects. Administration of amyl nitrite augmented peak diastolic and systolic graft blood velocity within 10 seconds and maximal blood velocities were recorded between 8 and 60 seconds after inhalation. Control mean (+/- 1 S.D.) bypass graft blood velocity was 25 +/- 10 cm. per second and after amyl nitrite 46 +/- 14 cm. per second, resulting in an average 84 per cent rise of blood velocity. It is concluded that amyl nitrite increases aortocoronary bypass graft blood velocity, suggesting a possible enhancement of blood flow to the distal native circulation in patients so operated upon.
Authors:
A Benchimol; K B Desser; V Raizada
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  93     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1977 May 
Date Detail:
Created Date:  1977-05-27     Completed Date:  1977-05-27     Revised Date:  2006-02-27    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  592-5     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Amyl Nitrite / pharmacology*
Aorta
Blood Flow Velocity
Coronary Artery Bypass*
Coronary Circulation / drug effects
Humans
Male
Middle Aged
Regional Blood Flow / drug effects
Saphenous Vein / transplantation
Transplantation, Autologous
Chemical
Reg. No./Substance:
8017-89-8/Amyl Nitrite

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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