Document Detail

Effects of amnıotıc and maternal CD-146, TGF-β1, IL-12, IL-18 and Inf-γ, on adverse pregnancy outcome.
MedLine Citation:
PMID:  22913276     Owner:  NLM     Status:  Publisher    
Abstract Objective: Our aim was to determine the effects of maternal serum and amniotic fluid levels of cluster of differentiation 146 (CD-146), transforming growth factor (TGF)-β1, interleukin (IL)-12, IL-18, and interferon (IFN)-γ on intrauterine growth restriction and preterm labor. Methods: In this retrospective cohort study, we included pregnant women who underwent amniocentesis at Istanbul University Cerrahpasa Medical School. Women were followed up to labor. The study group comprised 23 women with adverse pregnancy outcomes (intrauterine growth restriction and preterm labor), and the control group comprised 105 women with normal pregnancy outcome. Results: The study group was further divided into two subgroups of preterm labor and intrauterine growth restriction. No significant differences were found for IL-12, IFN-γ, TGF-β1, or CD-146 levels in either plasma or amniotic fluid between the study and control groups.Serum IL-18 levels were similar, but the amniotic fluid level of IL-18 was significantly higher in the intrauterine growth restriction subgroup than that in the preterm labor subgroup and that in the control group (p < 0.01). Conclusions: Increased IL-18 level in amniotic fluid may be a predictor for intrauterine growth restriction. IL-12, IFN-γ, TGF-β1, and CD-146 were not related to adverse pregnancy outcome.
Tayfur Cift; Seyfettin Uludag; Yavuz Aydin; Ali Benian
Related Documents :
14586376 - Placental villitis of unclear etiology during ovum donor in vitro fertilization pregnancy.
465386 - Artificial insemination in denmark by frozen donor semen supplied from a central bank.
22681426 - Young adults' contraceptive knowledge, norms and attitudes: associations with risk of u...
22540326 - In vitro fertilization pregnancy rates in levothyroxine-treated women with hypothyroidi...
16274606 - Successful birth after injection of frozen human oocytes with frozen epididymal spermat...
11507706 - Maternally separated rats show deficits in maternal care in adulthood.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-22
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  -     ISSN:  1476-4954     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Obstetrics and Gynecology, Cerrahpasa Medical Faculty of Istanbul University, Istanbul, Turkey.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Synthesis, Cytotoxicity and Cell Death Profile of Polyaminoanthraquinones as Antitumor Agents.
Next Document:  Isolation of bacterial probiotic candidates from the gastrointestinal tract of rainbow trout, Oncorh...