Document Detail


Effects of aging and spinal degeneration on mechanical properties of lumbar supraspinous and interspinous ligaments.
MedLine Citation:
PMID:  14588267     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND CONTEXT: The effects of aging and spinal degeneration on the mechanical properties of spinal ligaments are still unknown, although there have been several studies demonstrating those of normal spinal ligaments. PURPOSE: To investigate the mechanical properties of the human posterior spinal ligaments in human lumbar spine, and their relation to age and spinal degeneration parameters. STUDY DESIGN/SETTING: Destructive uniaxial tensile tests were performed on the human supraspinous and interspinous ligaments at L4-5 level. Their mechanical properties were compared with age and spinal degeneration using several imaging modalities. PATIENT SAMPLE: Twenty-four patients with lumbar degenerative diseases on whom posterior surgeries were performed, with the age ranging from 18 to 85 years. OUTCOME MEASURES: The ultimate load and elastic stiffness as structural properties, the degree of disc degeneration, range of segmental motion, the disc height, disc space narrowing ratio and degree of facet degeneration as the parameters of spinal degeneration. METHODS: Twenty-four supraspinous and interspinous ligaments at the L4-5 level were obtained from posterior surgeries of patients with lumbar degenerative disease. The mechanical tests of bone-ligament-bone complexes were performed in a uniaxial tensile fashion with a specially designed clamp device. The ultimate load and elastic stiffness were calculated as structural properties. The degree of disc degeneration, range of segmental motion, the disc height, disc space narrowing ratio and degree of facet degeneration were examined by using radiographs, computed tomography and magnetic resonance imaging. RESULTS: The average and SD value of ultimate load, elastic stiffness, tensile strength and elastic modulus were 203+/-102.9 N, 60.6+/-36.7 N/mm, 1.2+/-0.6 Mpa and 3.3+/-2.1 Mpa, respectively. A significant negative correlation was found between age and tensile strength (p= 0.02). The specimens with facet degeneration showed lower values in tensile strength and elastic modulus than those without facet degeneration (p<0.04). However, no correlation was found between disc-related parameters and tensile strength. CONCLUSIONS: The mechanical strength of human lumbar posterior spinal ligaments decreases with age and facet degeneration, particularly in the ligament substance.
Authors:
Takahiro Iida; Kuniyoshi Abumi; Yoshihisa Kotani; Kiyoshi Kaneda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The spine journal : official journal of the North American Spine Society     Volume:  2     ISSN:  1529-9430     ISO Abbreviation:  Spine J     Publication Date:    2002 Mar-Apr
Date Detail:
Created Date:  2003-10-31     Completed Date:  2003-12-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  101130732     Medline TA:  Spine J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  95-100     Citation Subset:  IM    
Affiliation:
Department of Orthopaedic Surgery, Hokkaido University Graduate School of Medicine, Kita-15, Nishi-7, Kitaku, Sapporo, 060-8638, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Aging / pathology*,  physiology*
Elasticity
Humans
Ligaments / pathology*,  physiopathology*
Lumbar Vertebrae / physiopathology*
Middle Aged
Tensile Strength
Weight-Bearing

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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