Document Detail


The postictal state: effects of age and underlying brain dysfunction.
MedLine Citation:
PMID:  20724220     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
There is relatively little information on the underlying parameters that affect clinical features of the postictal period. Age-related physiological changes, including alterations in cerebral blood flow and metabolism, neurotransmitter function, and responses of the brain to seizure activity may affect postictal clinical phenomena. Some conclusions can be drawn. Elderly adults and children, particularly in the presence of diffuse cerebral dysfunction, may have more prolonged postictal confusion. Postictal dysphasia strongly suggests a dominant hemisphere focus, more often temporal, and Todd's paralysis is always contralateral to the epileptogenic zone. Much additional information could be derived from the vast amount of video/EEG monitoring data available.
Authors:
William H Theodore
Publication Detail:
Type:  Journal Article; Review     Date:  2010-08-17
Journal Detail:
Title:  Epilepsy & behavior : E&B     Volume:  19     ISSN:  1525-5069     ISO Abbreviation:  Epilepsy Behav     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-11     Completed Date:  2011-01-21     Revised Date:  2012-04-27    
Medline Journal Info:
Nlm Unique ID:  100892858     Medline TA:  Epilepsy Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  118-20     Citation Subset:  IM    
Copyright Information:
Published by Elsevier Inc.
Affiliation:
Clinical Epilepsy Section, National Institutes of Health, Bethesda, MD 20892, USA. theodorw@ninds.nih.gov
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Aged
Amnesia, Anterograde / etiology,  metabolism,  physiopathology
Brain / metabolism,  physiopathology*
Child
Humans
Paralysis / etiology,  metabolism,  physiopathology
Seizures / complications*,  metabolism,  physiopathology*
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