Document Detail


Effects of aerobic exercise on metabolic syndrome improvement in response to weight reduction.
MedLine Citation:
PMID:  17925474     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The objective was to test effects of aerobic exercise training on metabolic syndrome (MetSyn) improvement in response to weight reduction. RESEARCH METHODS AND PROCEDURES: A total of 459 overweight and obese women (age, 49 +/- 9 years; BMI, 28 +/- 3 kg/m(2)) were recruited for a baseline examination to test the relationship between cardiorespiratory fitness and metabolic syndrome prevalence; among these, 67 subjects with MetSyn were treated with 14-week weight-loss programs, which included low-calorie diet and aerobic exercise. The MetSyn was defined according to the Examination Committee of Criteria for "Metabolic Syndrome" in Japan. Maximal oxygen uptake (Vo(2max)) during a maximal cycling test was measured as an index of cardiorespiratory fitness at baseline and after the intervention. RESULTS: In the baseline examination, age- and BMI-adjusted odds ratios for MetSyn prevalence in the low, middle, and upper thirds of Vo(2max) were 1.0 (referent), 0.50 (95% confidence interval, 0.26 to 0.95), and 0.39 (95% confidence interval, 0.14 to 0.96), respectively (linear trend, p = 0.02). The adjusted odds ratios for MetSyn improvement in the two interventions with diet alone and diet plus exercise were 1.0 and 3.68 (95% confidence interval, 1.02 to 17.6; p = 0.04), respectively. DISCUSSION: These results suggest that adding aerobic exercise training to a dietary weight-reduction program further improves MetSyn (adjusted odds ratio, 3.68) in obese women, compared with diet alone. Further studies on an association between Vo(2max) change and MetSyn improvement are needed.
Authors:
Tomohiro Okura; Yoshio Nakata; Kazunori Ohkawara; Shigeharu Numao; Yasutomi Katayama; Tomoaki Matsuo; Kiyoji Tanaka
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Obesity (Silver Spring, Md.)     Volume:  15     ISSN:  1930-7381     ISO Abbreviation:  Obesity (Silver Spring)     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-10-10     Completed Date:  2008-01-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101264860     Medline TA:  Obesity (Silver Spring)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2478-84     Citation Subset:  IM    
Affiliation:
Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan. okura@taiiku.tsukuba.ac.jp
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MeSH Terms
Descriptor/Qualifier:
Adult
Asian Continental Ancestry Group
Blood Glucose / analysis
Body Mass Index
Exercise*
Female
Humans
Japan
Lipids / blood
Metabolic Syndrome X / complications,  diet therapy,  therapy*
Middle Aged
Obesity / complications,  diet therapy,  therapy*
Treatment Outcome
Weight Loss*
Chemical
Reg. No./Substance:
0/Blood Glucose; 0/Lipids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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