| Effects of aerobic exercise on C-reactive protein, body composition, and maximum oxygen consumption in adults: a meta-analysis of randomized controlled trials. | |
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MedLine Citation:
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PMID: 17046553 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of the study was to use the meta-analytic approach to examine the effects of aerobic exercise on C-reactive protein (CRP) in adults. Secondary outcomes included changes in body weight in kilograms, percentage of body fat, and maximum oxygen consumption (VO2max) in mL kg(-1) min(-1). Studies were retrieved using computerized literature searches, cross-referencing, and hand searching. Inclusion criteria were assessment of CRP in randomized controlled trials published in the English language between January 1, 1990, and January 1, 2006. Studies were also limited to aerobic exercise interventions lasting 4 weeks or more in adults 18 years or older. Five studies representing 323 male and female subjects (171 exercise, 152 control) and 6 outcomes for CRP were available for pooling. A nonsignificant reduction of approximately 3% was observed for CRP in the exercise groups (mean +/- SEM, -0.11 +/- 0.14 mg/L; 95% confidence interval [CI], -0.39 to 0.17 mg/L) using a random-effects model. Statistically significant reductions of approximately 4% were found for body weight (mean +/- SEM, -3.4 +/- 1.0 kg; 95% CI, -5.3 to -1.5 kg) and percentage of body fat (mean +/- SEM, -1.4% +/- 0.4%; 95% CI, -2.3% to -0.6%), whereas a statistically significant increase of 12% was found for VO2max (mean +/- SEM, 3.3 +/- 0.9 mL kg(-1) min(-1); 95% CI, 1.5 to 5.1 mL kg(-1) min(-1)). The results of our study suggest that aerobic exercise does not reduce CRP levels in adults, but does improve measures of body composition and physical fitness. |
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Authors:
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George A Kelley; Kristi S Kelley |
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Publication Detail:
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Type: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Metabolism: clinical and experimental Volume: 55 ISSN: 0026-0495 ISO Abbreviation: Metab. Clin. Exp. Publication Date: 2006 Nov |
Date Detail:
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Created Date: 2006-10-18 Completed Date: 2006-11-21 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0375267 Medline TA: Metabolism Country: United States |
Other Details:
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Languages: eng Pagination: 1500-7 Citation Subset: IM |
Affiliation:
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Department of Community Medicine, School of Medicine, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown, WV 26506-9190, USA. gkelley@hsc.wvu.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Body Composition / physiology* Body Weight / physiology C-Reactive Protein / physiology* Cardiovascular Diseases / prevention & control Exercise / physiology* Female Humans Male Middle Aged Oxygen Consumption / physiology* Randomized Controlled Trials as Topic |
| Chemical | |
Reg. No./Substance:
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9007-41-4/C-Reactive Protein |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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