Document Detail

Effects of acute tobacco abstinence in adolescent smokers compared with nonsmokers.
MedLine Citation:
PMID:  18565437     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Abstinence effects such as nicotine withdrawal and mood changes contribute to the maintenance of cigarette smoking in adult smokers, and emerging reports on adolescent smokers suggest they may experience similar subjective effects when deprived. This study aimed to prospectively document tobacco abstinence-induced changes during the first 48 hours of abstinence in adolescent smokers compared with nonsmokers, to distinguish effects distinct from typical adolescent lability.
METHODS: Fifty-seven adolescent smokers and 44 adolescent nonsmokers were assessed during a 48-hour inpatient session. Characteristic nicotine withdrawal symptoms, cravings for cigarettes, and mood symptoms were measured at 13 time points following initiation of abstinence.
RESULTS: The only abstinence-related effects observed were changes in craving for tobacco and feelings of anger. Tobacco craving increased and peaked quickly following initiation of abstinence and displayed a slight decrease toward the end of the 48-hour abstinence period, while anger symptoms peaked after a more prolonged abstinence. Overall, smokers' symptoms and cravings were positively associated with amount of daily smoking but not with reports of dependence or biological measures of extent of use.
CONCLUSIONS: We observed that among adolescent smokers, the primary effects associated with abstinence from cigarettes are relatively minimal, and include a heightened and persistent craving to smoke and increases in anger. Although smokers had greater negative mood symptoms compared with nonsmokers, the presence and severity of most of these symptoms appear to be minimally altered by abstinence and not associated with dependency or biological indicators of amount of tobacco use.
Anne E Smith; Dana A Cavallo; Tricia Dahl; Ran Wu; Tony P George; Suchitra Krishnan-Sarin
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural     Date:  2008-03-06
Journal Detail:
Title:  The Journal of adolescent health : official publication of the Society for Adolescent Medicine     Volume:  43     ISSN:  1879-1972     ISO Abbreviation:  J Adolesc Health     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-20     Completed Date:  2008-07-21     Revised Date:  2013-06-05    
Medline Journal Info:
Nlm Unique ID:  9102136     Medline TA:  J Adolesc Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  46-54     Citation Subset:  IM    
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA.
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MeSH Terms
Connecticut / epidemiology
Interviews as Topic
Prospective Studies
Severity of Illness Index
Smoking / epidemiology*
Substance Withdrawal Syndrome / diagnosis,  epidemiology,  physiopathology*
Grant Support

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