| Effects of acute ingestion of salbutamol during submaximal exercise. | |
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MedLine Citation:
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PMID: 11071049 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To assess the eventual effects of acute oral salbutamol intake on performance and metabolism during submaximal exercise, nine healthy volunteers completed two cycling trials at a power corresponding to 80-85% VO2max, after either placebo (Pla) or salbutamol (Sal, 6 mg) treatment, according to a double-blind randomized protocol. Blood samples were collected both at rest and during exercise (5 min-, 10 min-, 15 min-exhaustion) for C-peptide, FFA, lactate and blood glucose measurements. Cycling performance was significantly improved in the Sal vs. Pla trials (p < 0.05). After Sal intake, resting C-peptide, lactate, FFA and blood glucose values were higher whereas exercise lactate and free fatty acid concentrations were greater during and at the conclusion of the exercise period (p < 0.05). These results suggest that acute salbutamol ingestion improved performance during submaximal exercise probably through an enhancement of the overall contribution to energy production from both aerobic and anaerobic metabolisms. |
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Authors:
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K Collomp; R Candau; R Collomp; J Carra; F Lasne; C Préfaut; J De Ceaurriz |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: International journal of sports medicine Volume: 21 ISSN: 0172-4622 ISO Abbreviation: Int J Sports Med Publication Date: 2000 Oct |
Date Detail:
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Created Date: 2001-02-23 Completed Date: 2001-03-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8008349 Medline TA: Int J Sports Med Country: GERMANY |
Other Details:
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Languages: eng Pagination: 480-4 Citation Subset: IM |
Affiliation:
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Laboratoire National de Dépistage du Dopage, Chatenay-Malabry, France. katia.collomp@staps.u-psud.fr |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Adrenergic beta-Agonists / administration & dosage* Adult Albuterol / administration & dosage* Bicycling Blood Glucose / analysis C-Peptide / blood Double-Blind Method Energy Metabolism / drug effects Exercise Tolerance / drug effects* Fatty Acids, Nonesterified / blood Humans Lactates / blood Male |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Agonists; 0/Blood Glucose; 0/C-Peptide; 0/Fatty Acids, Nonesterified; 0/Lactates; 18559-94-9/Albuterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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