Document Detail


Effects of acute hypoxia on the estimation of lactate threshold from ventilatory gas exchange indices during an incremental exercise test.
MedLine Citation:
PMID:  15588134     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to investigate the validity of non-invasive lactate threshold estimation using ventilatory and pulmonary gas exchange indices under condition of acute hypoxia. Seven untrained males (21.4+/-1.2 years) performed two incremental exercise tests using an electromagnetically braked cycle ergometer: one breathing room air and other breathing 12 % O2. The lactate threshold was estimated using the following parameters: increase of ventilatory equivalent for O2 (VE/VO2) without increase of ventilatory equivalent for CO2 (VE/VCO2). It was also determined from the increase in blood lactate and decrease in standard bicarbonate. The VE/VO2 and lactate increase methods yielded the respective values for lactate threshold: 1.91+/-0.10 l/min (for the VE/VO2) vs. 1.89+/-0.1 l/min (for the lactate). However, in hypoxic condition, VE/VO2 started to increase prior to the actual threshold as determined from blood lactate response: 1.67+/-0.1 l/min (for the lactate) vs. 1.37+/-0.09 l/min (for the VE/VO2) (P=0.0001), i.e. resulted in pseudo-threshold behavior. In conclusion, the ventilatory and gas exchange indices provide an accurate lactate threshold. Although the potential for pseudo-threshold behavior of the standard ventilatory and gas exchange indices of the lactate threshold must be concerned if an incremental test is performed under hypoxic conditions in which carotid body chemosensitivity is increased.
Authors:
O Ozcelik; H Kelestimur
Related Documents :
24531204 - Is exercise training safe and beneficial in patients receiving left ventricular assist ...
23470304 - Diagnosis of arrhythmias in athletes using leadless, ambulatory heart rate monitors.
23104594 - Habitual exercise correlates with exercise performance in patients with conotruncal abn...
2482714 - Simple kinetic model for the study of lactate metabolic adaptation to exercise in sport...
21036024 - Cost-saving effect of supervised exercise associated to copd self-management education ...
16578994 - Inhalation injury after capsaicin exposure.
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Validation Studies    
Journal Detail:
Title:  Physiological research / Academia Scientiarum Bohemoslovaca     Volume:  53     ISSN:  0862-8408     ISO Abbreviation:  Physiol Res     Publication Date:  2004  
Date Detail:
Created Date:  2004-12-13     Completed Date:  2005-05-31     Revised Date:  2008-04-02    
Medline Journal Info:
Nlm Unique ID:  9112413     Medline TA:  Physiol Res     Country:  Czech Republic    
Other Details:
Languages:  eng     Pagination:  653-9     Citation Subset:  IM    
Affiliation:
Department of Physiology, Firat University, Faculty of Medicine, Elazig, Turkey. oozcelik@firat.edu.tr
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Anaerobic Threshold*
Anoxia / physiopathology*
Exercise Test / methods*
Humans
Lactic Acid / blood*
Male
Oxygen Consumption*
Pulmonary Gas Exchange*
Reproducibility of Results
Sensitivity and Specificity
Statistics as Topic
Chemical
Reg. No./Substance:
50-21-5/Lactic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Dipyridamole inhibits hydroxylamine augmented nitric oxide (NO) production by activated polymorphonu...
Next Document:  Changes of dopamine-beta-hydroxylase activity during ontogenesis in healthy subjects and in an exper...