Document Detail

Effects of acute administration of taurocholic and taurochenodeoxycholic acid on biliary lipid excretion in the rat.
MedLine Citation:
PMID:  1250846     Owner:  NLM     Status:  MEDLINE    
Comparison of the effects of biliary lipid excretion produced by infusion of taurochenodeoxycholate and taurocholate showed no significant difference when the bile acids were infused for a relatively short period of time. Cholesterol excretion rates measured during depletion of the bile acid pool were significantly higher than cholesterol excretion rates measured during infusion of bile acids at various rates. These data indicate that there is some mechanism in addition to bile acid excretion that is responsible for biliary excretion of cholesterol when the enterohepatic circulation is intact.
D L Eaton; C D Klaassen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)     Volume:  151     ISSN:  0037-9727     ISO Abbreviation:  Proc. Soc. Exp. Biol. Med.     Publication Date:  1976 Jan 
Date Detail:
Created Date:  1976-04-09     Completed Date:  1976-04-09     Revised Date:  2007-11-02    
Medline Journal Info:
Nlm Unique ID:  7505892     Medline TA:  Proc Soc Exp Biol Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  198-202     Citation Subset:  IM    
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MeSH Terms
Bile / metabolism*
Bile Acids and Salts / metabolism
Chenodeoxycholic Acid / analogs & derivatives*,  pharmacology
Cholesterol / metabolism*
Phospholipids / metabolism*
Taurine / analogs & derivatives
Taurocholic Acid / pharmacology*
Reg. No./Substance:
0/Bile Acids and Salts; 0/Phospholipids; 107-35-7/Taurine; 474-25-9/Chenodeoxycholic Acid; 57-88-5/Cholesterol; 81-24-3/Taurocholic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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