Document Detail

Effects of acidemia and sodium bicarbonate therapy in advanced cardiac life support.
MedLine Citation:
PMID:  6089619     Owner:  NLM     Status:  MEDLINE    
Cardiac output using the currently recommended closed-chest cardiopulmonary resuscitation (CPR) technique is marginal (less than 30% of control), and eventually will result in tissue hypoperfusion and lactic acidemia. Intermittent sodium bicarbonate administration currently is recommended for treatment of this metabolic acidemia, and based on available data recommended dosages are empiric but sound. In this review the potential complications of acidemia and sodium bicarbonate administration are considered from the viewpoint of resuscitation outcome. In our opinion, available data are limited, and further evaluation and consideration of sodium bicarbonate requirements in the resuscitation setting are required.
J T Niemann; J P Rosborough
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of emergency medicine     Volume:  13     ISSN:  0196-0644     ISO Abbreviation:  Ann Emerg Med     Publication Date:  1984 Sep 
Date Detail:
Created Date:  1984-10-24     Completed Date:  1984-10-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8002646     Medline TA:  Ann Emerg Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  781-4     Citation Subset:  AIM; IM    
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MeSH Terms
Acidosis, Respiratory / prevention & control
Bicarbonates / adverse effects*
Heart Arrest* / therapy
Hydrogen-Ion Concentration
Lactates / blood*
Sodium Bicarbonate
Reg. No./Substance:
0/Bicarbonates; 0/Lactates; 144-55-8/Sodium Bicarbonate

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