| [Effects of Xuefu Zhuyu Oral Liquid on hemorheology in patients with blood-stasis syndrome due to coronary disease and their relationship with human platelet antigen-3 polymorphism]. | |
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MedLine Citation:
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PMID: 18990338 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate the effects of Xuefu Zhuyu Oral Liquid, a compound traditional Chinese herbal medicine for resolving stagnation, on hemorheology in the patients with blood-stasis syndrome due to coronary disease and their relationship with human platelet antigen-3 (HPA-3) polymorphism of membrane glycoprotein IIb (GPIIb). METHODS: Thirty-two patients with blood-stasis syndrome due to coronary disease were selected in this study. Blood-stasis syndrome scoring was performed and hemorheological parameters were measured in all subjects before and after Xuefu Zhuyu Qral Liquid treatment. The genotypes of GPIIb HPA-3 were determined by TaqMan probe technology. RESULTS: The hemorheology was improved in the patients with blood-stasis syndrome due to coronary heart disease after the treatment. There were significant differences in the whole blood viscosity, deformation index of red blood cells and scores of blood-stasis syndrome between the patients carrying AC plus CC and the patients carrying AA after the treatment (P<0.05). CONCLUSION: Xuefu Zhuyu Oral Liquid can improve clinical symptoms and hemorheology in the patients with blood-stasis syndrome due to coronary heart disease, which is related to GPIIb HPA-3 polymorphism. |
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Authors:
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Mei Xue; Ke-ji Chen; Xiao-juan Ma; Jian-gang Liu; Yue-rong Jiang; Yu Miao; Hui-jun Yin |
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Publication Detail:
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Type: English Abstract; Journal Article |
Journal Detail:
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Title: Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine Volume: 6 ISSN: 1672-1977 ISO Abbreviation: Zhong Xi Yi Jie He Xue Bao Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101199657 Medline TA: Zhong Xi Yi Jie He Xue Bao Country: China |
Other Details:
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Languages: chi Pagination: 1129-35 Citation Subset: IM |
Affiliation:
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Laboratory of Cardiovascular Diseases, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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