| Effects of Tissue Fixation on Light Scatter by PCO. | |
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MedLine Citation:
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PMID: 22251401 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Purpose: To investigate whether light scattering of posterior capsule opacifications (PCOs) changes after fixation with paraformaldehyde (PFA). Methods: The intraocular lens with the lens capsule were extracted from pseudophakic donor eyes. Images of the extracted sample were acquired pre and post PFA-fixation using a dark field microscope. Light scatter intensity was measured for different regions pre and post fixation. Results: The regression lines between the light intensities measured pre and post fixation for the three color channels showed the same slope of 0.96. Also the correlation coefficients were the same for the three color channels, namely 0.97. Conclusions: Scattering intensities of PCO tissue pre and post fixation are quantitatively similar. The effects of fixation on the optical properties of PCO can be considered small. |
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Authors:
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Bastiaan Kruijt; Thomas Jtp van den Berg |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current eye research Volume: 37 ISSN: 1460-2202 ISO Abbreviation: Curr. Eye Res. Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-01-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8104312 Medline TA: Curr Eye Res Country: England |
Other Details:
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Languages: eng Pagination: 159-61 Citation Subset: IM |
Affiliation:
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Netherlands Institute for Neuroscience, Royal Netherlands Academy for Arts and Sciences , Amsterdam , The Netherlands. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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