Document Detail


Effects of subtotal gastrectomy and Roux-en-Y gastrojejunostomy on the clinical outcome of type 2 diabetes mellitus.
MedLine Citation:
PMID:  20863527     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
BACKGROUND: To investigate the effects of subtotal gastrectomy and Roux-en-Y gastrojejunostomy on the clinical outcome of patients with type 2 diabetes mellitus (T2DM). METHODS: We performed retrospective analysis of 21 patients with T2DM operated due to stomach cancer and upper gastrointestinal tract ulcer between January 2001 and June 2008. RESULTS: The body mass index (BMl) of all patients was <30 kg/m(2). The mean postoperative follow-up period was 26.6 mo (range, 6 mo-5 y). Subtotal gastrectomy and Roux-en-Y gastrojejunostomy remarkably lowered the levels of fasting plasma glucose (FPG), 2 h postprandial plasma glucose (2hPG), and glycated hemoglobin (HbA1c). Overall, 12 patients (57.1%) achieved adequate glycemic control (HbA1c < 7%) without antidiabetic medication and five patients (23.8%) showed good improvement. The total effectiveness rate of the surgery in T2DM patients was 81.0%. CONCLUSION: Subtotal gastrectomy and Roux-en-Y gastrojejunostomy appear to be effective treatment modalities for controlling T2DM in patients with BMl <30 kg/m(2). However, more studies with long follow-up period and large number of patients are necessary to clarify the benefits of this procedure.
Authors:
Juntao Yang; Chunxue Li; Hongming Liu; Hongguang Gu; Ping Chen; Baohua Liu
Related Documents :
20414197 - Body composition and energy metabolism following roux-en-y gastric bypass surgery.
11775567 - Band erosion: incidence, etiology, management and outcome after banded vertical gastric...
21596877 - Obesity does not influence the onset and offset of sevoflurane effect as measured by th...
17103267 - Impact of morbid obesity on outcome of laparoscopic splenectomy.
10860067 - A review of changes in lower arch alignment from seven to fifty years.
7726267 - Single oral dose fluconazole compared with conventional clotrimazole topical therapy of...
Publication Detail:
Type:  Journal Article     Date:  2010-07-30
Journal Detail:
Title:  The Journal of surgical research     Volume:  164     ISSN:  1095-8673     ISO Abbreviation:  J. Surg. Res.     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-10-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376340     Medline TA:  J Surg Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e67-71     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Inc. All rights reserved.
Affiliation:
Department of Hepatobiliary Surgery, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  IL-10 polymorphism associated with decreased risk for mortality after burn injury.
Next Document:  Discordant activation of gene promoters for matrix metalloproteinases and tissue inhibitors of the m...