Document Detail


Effects of submaximal exercise on blood rheology and sympathetic nerve activity.
MedLine Citation:
PMID:  20190425     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: To explore the acute effects of submaximal exercise on blood rheology and sympathetic nerve activity.
METHODS AND RESULTS: The effects of exercise (20 or 80 Watts (W)) on blood rheology and sympathetic nerve activity were assessed in 10 healthy Japanese men. Blood sampling and heart rate variability (HRV) recording were performed during 20-min supine rest and standing ergometric exercise (20 W for 10 min, 80 W for 10 min) and recovery. Blood passage time across the microchannels (diameter, 7 microm) as a parameter of blood rheology, and the number of adhesive leukocytes on microchannel terraces as a parameter of leukocyte activation were measured. Sympathetic nerve activity was evaluated by plasma noradrenalin levels and the ratio of low-frequency (LF)/high-frequency (HF) by spectral analysis of HRV. Compared with values while supine at rest, significant increases in hematocrit, leukocyte count, noradrenalin level and blood passage time were seen after strenuous ergometer exercise at 80 W (P<0.01 each). The LF/HF ratio and nitric oxide metabolites tended to be increased with 80 W exercise.
CONCLUSIONS: Strenuous exercise dynamically alters blood rheological parameters, probably by changes in hematocrit and sympathetic nerve activity.
Authors:
Nahoko Ikeda; Takanori Yasu; Ken Tsuboi; Yoshitaka Sugawara; Norifumi Kubo; Tomio Umemoto; Kenshiro Arao; Masanobu Kawakami; Shin-ichi Momomura
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Publication Detail:
Type:  Journal Article     Date:  2010-02-27
Journal Detail:
Title:  Circulation journal : official journal of the Japanese Circulation Society     Volume:  74     ISSN:  1347-4820     ISO Abbreviation:  Circ. J.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-26     Completed Date:  2010-07-15     Revised Date:  2011-02-18    
Medline Journal Info:
Nlm Unique ID:  101137683     Medline TA:  Circ J     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  730-4     Citation Subset:  IM    
Affiliation:
First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Circulation / physiology*
Exercise / physiology*
Heart Rate / physiology
Hematocrit
Humans
Leukocyte Count
Male
Middle Aged
Nitric Oxide / metabolism
Norepinephrine / blood
Plasma Volume / physiology*
Posture / physiology*
Rheology
Sympathetic Nervous System / physiology*
Chemical
Reg. No./Substance:
10102-43-9/Nitric Oxide; 51-41-2/Norepinephrine
Comments/Corrections
Comment In:
Circ J. 2010 Jul;74(7):1497; author reply 1498   [PMID:  20508378 ]

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