| Effects of Shao-Fu-Zhu-Yu-Tang on motility of human sperm. | |
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MedLine Citation:
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PMID: 14587880 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Shao-Fu-Zhu-Yu-Tang (SFZYT) is reportedly beneficial to sperm. In this study, we examined sperm acrosomal activity and serum free radical changes to evaluate the possible mechanism of SFZYT. A clinical study evaluated the sperm count and motility in 36 patients with chronic prostatitis before and after treatment for 60 days. The results revealed a significant increase in sperm motility after treatment as evaluated by computer-assisted semen analysis (17.27 +/- 9.00 versus 28.29 +/- 10.00, p < 0.01). An increase in sperm quantity and quality was observed by count and morphology with a high-powered intravital microscope. To gain an understanding of the mechanisms that caused this effect, we assessed sperm acrosin activity levels before (10.6 micro lu/10(6)) and after medication (28.6 micro lu/10(6)) (p < 0.01). The levels of the free radicals was relatively higher before medication, 2144, compared to a normal value of 780 after medication (p < 0.01). In conclusion, SFZYT increased the motility and quality of human semen and this increase is related to an increase in sperm acrosin activity. SFZYT also works as a sperm antioxidant and antiaging agent. |
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Authors:
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Ching-Chiang Yang; Jung-Chou Chen; Guang-Wei Chen; Yi-shuan Chen; J G Chung |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of Chinese medicine Volume: 31 ISSN: 0192-415X ISO Abbreviation: Am. J. Chin. Med. Publication Date: 2003 |
Date Detail:
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Created Date: 2003-10-31 Completed Date: 2004-02-19 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7901431 Medline TA: Am J Chin Med Country: United States |
Other Details:
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Languages: eng Pagination: 573-9 Citation Subset: IM |
Affiliation:
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Department of Urology, China Medical University Hospital Taichung 400, Taiwan, ROC. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acrosin
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metabolism Adult Antioxidants / administration & dosage, pharmacology*, therapeutic use Drugs, Chinese Herbal / administration & dosage, pharmacology*, therapeutic use Humans Male Phytotherapy* Plant Extracts / administration & dosage, pharmacology, therapeutic use Plants, Medicinal* Sperm Motility / drug effects* Spermatozoa / drug effects*, metabolism |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Drugs, Chinese Herbal; 0/Plant Extracts; EC 3.4.21.10/Acrosin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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