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Effects of Scaling and Root Planing on Clinical Response and Serum Levels of Adipocytokines in Obese Patients With Chronic Periodontitis.
MedLine Citation:
PMID:  25119561     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background: Despite several investigations suggesting that obesity is a risk indicator for periodontitis, little is known about the impact of obesity on periodontal treatment response. The aim of this study was to evaluate the effects of scaling and root planing (SRP) on clinical parameters and circulating levels of leptin and adiponectin in obese patients with chronic periodontitis (CP). Methods: Twenty-four obese and 24 non-obese patients with CP were submitted to SRP. Clinical parameters were assessed at baseline, 3 and 6 months post-therapy. Serum levels of leptin and adiponectin were evaluated at all time points, using enzyme linked immunosorbent assay. Results: SRP improved the clinical parameters of both groups at 3 and 6 months (p<0.05). Nonetheless, the non-obese patients presented a lower mean probing depth (PD) at 6 months post-therapy and a greater reduction in PD from baseline to 6 months in the full-mouth analysis (primary outcome variable) and in initially deep sites (p<0.05). Leptin serum levels were higher in obese than non-obese patients at all time-points (p<0.05). No changes in the serum levels of leptin and adiponectin were observed in obese and non-obese groups after therapy (p>0.05). Conclusion: Obese patients with CP presented lower reductions in PD than non-obese patients at 6 months after SRP. Furthermore, the treatment did not affect the circulating levels of leptin and adiponectin in any group.
Authors:
Tiago Eduardo Dias Gonçalves; Magda Feres; Glaucia Santos Zimmermann; Marcelo Faveri; Luciene Cristina Figueiredo; Paloma Gralha Braga; Poliana Mendes Duarte
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-8-14
Journal Detail:
Title:  Journal of periodontology     Volume:  -     ISSN:  1943-3670     ISO Abbreviation:  J. Periodontol.     Publication Date:  2014 Aug 
Date Detail:
Created Date:  2014-8-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-12     Citation Subset:  -    
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