| Effects of Pycnoporellus fulgens (Fr.) Donk crude extract on Candida glabrata ultrastructure. | |
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MedLine Citation:
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PMID: 10424096 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Among antifungal products of natural origin, Pycnoporellus fulgens (Fr) Donk, is active against pathogenic yeasts. Our study was carried out to observe the ultrastructural modifications produced by P. fulgens crude extract on Candida glabrata. Yeasts were submitted to different concentrations (50, 100, 200, 400 micrograms ml-1) for 72 h under constant stirring at 35 degrees C. Transmission electron microscopy revealed that the extract acted on the cell envelope (cell wall and plasmalemma). Cell divisions were also affected by thickening of the septum (50 micrograms ml-1) and a deficiency in the daughter cell wall texture. The extent of the antifungal effect clearly depended on the extract concentration. |
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Authors:
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J Moulin-Traffort; M D Steinmetz; J P Rascol; P Regli |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Mycoses Volume: 42 ISSN: 0933-7407 ISO Abbreviation: Mycoses Publication Date: 1999 |
Date Detail:
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Created Date: 1999-08-19 Completed Date: 1999-08-19 Revised Date: 2000-12-18 |
Medline Journal Info:
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Nlm Unique ID: 8805008 Medline TA: Mycoses Country: GERMANY |
Other Details:
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Languages: eng Pagination: 273-9 Citation Subset: IM |
Affiliation:
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Laboratoire de Botanique, Cryptogamie et Biologie Cellulaire, Faculté de Pharmacie, Université de la Méditerranée, Marseille, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antifungal Agents
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pharmacology* Candida / drug effects*, ultrastructure Microbial Sensitivity Tests Microscopy, Electron Polyporaceae / chemistry* Temperature Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Antifungal Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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