| Effects of Proton Pump Inhibitors on Pediatric Inflammatory Esophagogastric Polyps. | |
| | |
MedLine Citation:
|
PMID: 22248910 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Background: The aim of this study was to investigate the effects of proton pump inhibitors on symptomatic inflammatory esophagogastric polyps (IEPs) in a pediatric cohort and to determine the optimal duration of treatment. Methods: The 11 patients with IEPs were managed with lansoprazole. Follow-up endoscopies were performed at 2 and 6 months after the start of medication. Medication was discontinued when the clinical symptoms completely resolved and the polyp size was reduced by more than 50% compared to the initial size. Results:The initial polyp size was 13.7 ± 3.3 mm. After 2 months of medication, the polyp size was reduced to 8.0 ± 5.8 mm. At 6 months, the polyp size was 4.7 ± 2.2 mm. The mean duration of medication was 4.8 ± 2.1 months. The duration of medication and the change in the polyp size appeared to have a linear correlation (p < 0.001). According to the formula used to calculate polyp size, the optimal duration of treatment was more than 7 months for complete resolution of the polyps. Conclusions: Proton pump inhibitor was effective for the treatment of IEPs. About 5 months of lansoprazole was adequate to treat IEPs in children. The optimal duration for complete resolution of the polyp might be more than 7 months. |
| | |
Authors:
|
Kyong Eun Choi; Mi Jin Kim; Ji Hyuk Lee; Jong Seung Lee; Jee Hyun Lee; Yon Ho Choe |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-13 |
Journal Detail:
|
Title: Digestion Volume: 85 ISSN: 1421-9867 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-17 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0150472 Medline TA: Digestion Country: - |
Other Details:
|
Languages: ENG Pagination: 179-184 Citation Subset: - |
Copyright Information:
|
Copyright © 2012 S. Karger AG, Basel. |
Affiliation:
|
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: CNT loading into cationic cholesterol suspensions show improved DNA binding and serum stability and ...
Next Document: SFRP1 promoter methylation and expression in human trabecular meshwork cells.