| Effects of Pasteurization on Adiponectin and Insulin Concentrations in Donor Human Milk. | |
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MedLine Citation:
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PMID: 21587097 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Although pasteurization is recommended before distributing donor human milk in North America, limited data are available on its impact on metabolic hormones in milk. We aimed to investigate the effects of pasteurization on adiponectin and insulin concentrations in donor human milk. The study investigates concentrations of components in donor human milk before and after Holder pasteurization. Following the guidelines of the Human Milk Bank Association of North America, human milk samples were pooled to produce 17 distinct batches (4 individuals per batch) and pasteurized at 62.5°C for 30 minutes. Adiponectin, insulin, energy, fat, total protein and glucose concentrations were measured pre- and post-pasteurization. Pasteurization reduced milk adiponectin and insulin by 32.8% and 46.1%, respectively (both p<0.0001). Adiponectin and insulin were significantly correlated with energy and fat milk composition (r=0.36-0.47; all p<0.05). Pasteurization effects on milk hormone concentrations remained significant after adjusting for fat and energy (beta±SEM: -4.11±1.27, p=0.003 for adiponectin; -70.0±15.0, p<0.0001 for insulin). Holder pasteurization reduced adiponectin and insulin concentrations in donor human milk. In view of emerging knowledge on the importance of milk components, continued work to find the optimal pasteurization process which mitigates risks but promotes retention of bioactive components is needed. ABBREVIATIONS: |
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Authors:
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Sylvia H Ley; Anthony J Hanley; Debbie Stone; Deborah L Oʼconnor |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-16 |
Journal Detail:
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Title: Pediatric research Volume: - ISSN: 1530-0447 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0100714 Medline TA: Pediatr Res Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Nutritional Sciences [S.H.L., A.J.H., D.L.O.], University of Toronto, Toronto M5S 3E2, Canada; Department of Clinical Dietetics [D.S., D.L.O.], Physiology and Experimental Medicine Program [D.L.O.], Hospital for Sick Children, Toronto M5G 1X8, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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