| Effects of N-butyl-2-cyanoacrylate on high-level jejunojejunostomy. | |
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MedLine Citation:
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PMID: 19907184 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Morbidity and mortality due to anastomotic complications in gastrointestinal surgery remain important problems. The tissue adhesive N-butyl-2-cyanoacrylate (NB2CA) is used in many fields of surgery. This study was designed to assess the effects of NB2CA on high-level jejunojejunostomy. MATERIALS AND METHODS: Forty male albino Wistar rats were divided into 4 groups of 10 each. The groups were treated as follows: group 1 underwent only a jejunojejunostomy, group 2 underwent jejunojejunostomy followed by NB2CA application around the anastomosis, group 3 underwent jejunojejunostomy after a 60-min ischemia and a 60-min reperfusion, and group 4 underwent jejunojejunostomy after a 60-min ischemia and a 60-min reperfusion followed by NB2CA application around the anastomosis. At postoperative day 7, the subjects in all groups were sacrificed. Intra-abdominal adhesions, anastomotic complications and anastomotic burst pressures (ABP) were recorded. RESULTS: The analysis of all the groups for adhesion scores and ABP showed statistical significance (p < 0.001). CONCLUSIONS: The use of NB2CA had positive effects in terms of increasing ABP both with and without the initial ischemia- reperfusion insult. However, it had the adverse effect of significantly increasing the number of intra-abdominal adhesions. |
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Authors:
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C O Ensari; V Genc; A Cakmak; B Erkek; K Karayalcin |
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Publication Detail:
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Type: Journal Article Date: 2009-11-12 |
Journal Detail:
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Title: European surgical research. Europ?ische chirurgische Forschung. Recherches chirurgicales europ?ennes Volume: 44 ISSN: 1421-9921 ISO Abbreviation: Eur Surg Res Publication Date: 2010 |
Date Detail:
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Created Date: 2010-01-13 Completed Date: 2010-04-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0174752 Medline TA: Eur Surg Res Country: Switzerland |
Other Details:
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Languages: eng Pagination: 13-6 Citation Subset: IM |
Copyright Information:
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Copyright 2009 S. Karger AG, Basel. |
Affiliation:
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Department of Surgery, Ankara University Medical School, Ankara, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anastomosis, Surgical Animals Enbucrilate / therapeutic use* Jejunum / surgery* Male Postoperative Complications / prevention & control* Rats Rats, Wistar Tissue Adhesions / prevention & control* |
| Chemical | |
Reg. No./Substance:
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6606-65-1/Enbucrilate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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